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Pinacidil . monohydrate

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K⁺ channel activator

K⁺ channel activator. Antihypertensive.

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Alternative Name	(±)-N-Cyano-N′-4-pyridinyl-N″-(1,2,2-trimethylpropyl)guanidine monohydrate
Appearance	White to off-white powder.
CAS	85371-64-8
Couple Target	Potassium channel
Couple Type	Activator
Formula	C₁₃H₁₉N₅. H₂O
MI	14: 7438
MW	245.3 . 18.0
Purity	≥98% (HPLC)
Solubility	Soluble in 100% ethanol (14mg/ml), DMSO (28mg/ml) or dilute aqueous acid; insoluble in water.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Keep under inert gas.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Pinacidil Monohydrate – A Novel Vasodilator: Review of Preclinical Pharmacology and Mechanism of Action: M.L. Cohen; Drug Dev. Res. 9, 249 (1986), Full Text

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