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Stable analog of pifithrin-α (Prod. No. BML-GR325), with biological properties similar to its parent compound, but with reduced cytotoxicity. Inhibitor of p53. Reversibly inhibits p53-dependent transactivation of p53-responsive genes and reversibly blocks p53-mediated apoptosis. Potent STAT6 transcriptional inhibitor. Increases apoptosis in target cells when used in combination with antimicrotubule agents.
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| Regulatory Status |
RUO – Research Use Only |
|---|
Related Products
| Alternative Name | 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone . HBr, PFT-α |
|---|---|
| CAS | 63208-82-2 |
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |