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Picotamide

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Thromboxane A₂ antagonist and TXA₂ synthase inhibitor

A dual activity thromboxane A₂ antagonist and TXA₂ synthase inhibitor. Clinically useful antiplatelet agent.

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Appearance	White solid.
CAS	32828-81-2
Couple Target	Prostanoid receptor, Thromboxane receptor, Thromboxane synthase
Couple Type	Inhibitor, Ligand
Formula	C₂₁H₂₀N₄O₃
MW	376.4
Purity	≥98% (HPLC)
Solubility	Soluble in DMSO (25mg/ml) or ethanol (25mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

The receptor antagonist picotamide inhibits adrenergic and thromboxane-induced contraction of hyperplastic human prostate smooth muscle: Hennenberg, M., Miljak, M., et al.; Am. J. Physiol. Renal Physiol. 305, F1383 (2013), Abstract

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