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A potent mycotoxin and anti-mitotic compound. Causes lupinosis in livestock fed infected lupins. Binds selectively to dimeric tubulin, inhibiting the formation of the microtubule spindle to block cell division. Binds to tubulin at a site overlapping that of vinblastine (Prod. No. ALX-350-257) and maytansine. Protects tubulin from decay.
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RUO – Research Use Only |
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