Perlecan is an extracellular matrix proteoglycan. It has a large core protein of 400-450kDa and is often produced with heparan sulfate side chains. Perlecan is found in basement membranes where it contributes to permeability charateristics, serves as a substrate for vascular cells, and binds growth factors involved in vascular remodelling.
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Last modified: May 29, 2024
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