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PATHO-GENE^® HPV type 31/33/51 probe

ENZ-32887

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A mixture of biotin-labeled HPV 31, HPV 33 and HPV 51-specific probes for in situ hybridization

The PATHO-GENE^® HPV type 31/33/51 probe is a mixture of biotin-labeled HPV 31, HPV 33 and HPV 51-specific probes in buffered formamide and hybridization enhancers.

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Application Notes	The ENZO PATHO-GENE^® HPV type 31/33/51 probe employs a mixture of the HPV 31, HPV 33 and HPV 51-specific probes that detect HPV types that have been associated with either condyloma or cervical intraepithelial neoplasia (CIN) and carcinoma in situ (CIS). The probe mixture is denatured and hybridized to the tissue section fixed and pretreated on the microscope slide. Specific hybridization between the HPV DNA probe and DNA in the specimen is determined by the detection of biotin.
Technical Info / Product Notes	HPV probe can be optimized for polymer detection system using diluent buffer, In situ hybridization buffer for HPV probes (Ready-to Use) (Prod. No. ENZ-33905). This product or the use of this product is covered by one or more Enzo patents, including, but not limited to the following: U.S. Patent No. 4,994,373; Canadian Patent No. 1,309,672; and patents pending.

Application Notes

The ENZO PATHO-GENE^® HPV type 31/33/51 probe employs a mixture of the HPV 31, HPV 33 and HPV 51-specific probes that detect HPV types that have been associated with either condyloma or cervical intraepithelial neoplasia (CIN) and carcinoma in situ (CIS). The probe mixture is denatured and hybridized to the tissue section fixed and pretreated on the microscope slide. Specific hybridization between the HPV DNA probe and DNA in the specimen is determined by the detection of biotin.

Technical Info / Product Notes

HPV probe can be optimized for polymer detection system using diluent buffer, In situ hybridization buffer for HPV probes (Ready-to Use) (Prod. No. ENZ-33905).

This product or the use of this product is covered by one or more Enzo patents, including, but not limited to the following: U.S. Patent No. 4,994,373; Canadian Patent No. 1,309,672; and patents pending.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least one year after receipt when stored as recommended.
Long Term Storage	+4°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Time course of juvenile onset recurrent respiratory papillomatosis caused by human papillomavirus: M. Hawkes, et al.; Pediatr. Infect. Dis. J. 27, 149 (2008), Abstract
p16 expression in relation to human papillomavirus in liquid-based cervical smears: B. Samama, et al.; Gynecol. Oncol. 109, 285 (2008), Abstract
p16 expression in relation to human papillomavirus in anogenital lesions: B. Samama, et al.; Hum. Pathol. 37, 513 (2006), Abstract
Detection of oncogenic virus genomes and gene products in lung carcinoma: L. Brouchet, et al.; Br. J. Cancer 92, 743 (2005), Abstract
Comparison of real-time PCR signal-amplified in situ hybridization and conventional PCR for detection and quantification of human papillomavirus in archival cervical cancer tissue: K. Biedermann, et al.; J. Clin. Microbiol. 42, 3758 (2004), Abstract
DNA copy number changes in cervical adenocarcinoma: A. Dellas, et al.; Clin. Cancer Res. 9, 2985 (2003), Abstract
Pearly penile papules: still no reason for uneasiness: C.J. Hogewoning, et al.; J. Am. Acad. Dermatol. 49, 50 (2003), Abstract
A cardiac allograft recipient with Bowen’s disease on a finger and concurrent perianal bowenoid papulosis: M. Ibe, et al.; J. Dermatol. 30, 389 (2003), Abstract
Morphologic and biologic studies on ten cases of verrucous carcinoma of the vulva supporting the theory of a discrete clinico-pathologic entity: M. Gualco, et al.; Int. J. Gynecol. Cancer 13, 317 (2003), Abstract
HPV DNA detection by in situ hybridization with catalyzed signal amplification on thin-layer cervical smears: B. Samama, et al.; J. Histochem. Cytochem. 50, 1417 (2002), Abstract

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PATHO-GENE^® HPV type 31/33/51 probe

ENZ-32887

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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PATHO-GENE® HPV type 31/33/51 probe

ENZ-32887

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