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PARP-2 (mouse) polyclonal antibody

ALX-210-899

6 citations

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This antibody is covered by our Worry-Free Guarantee.

Product Details

Alternative Name	Poly(ADP-ribose) polymerase-2
Application	ICC, IHC, IP, WB
Crossreactivity	Weakly cross-reacts with human PARP-2.
Formulation	Liquid. Antiserum containing 0.1% sodium azide.
Host	Rabbit
Immunogen	Recombinant mouse PARP-2 (poly(ADP-ribose) polymerase-2) fragment (aa 1-207) produced in Sf21 cells.
Recommendation Dilutions/Conditions	Immunocytochemistry (1:500-1:1,000)Immunohistochemistry (1:500-1:1,000)Immunoprecipitation (2µl per 100µg nuclear extract)Western Blot (1:2,000-1:5,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. Immunohistochemistry (frozen sections, or PFA-fixed cryosections)
Species Reactivity	Mouse
UniProt ID	O88554
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Use/Stability	Stable for 1 week when stored at +4°C.
Handling	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
Short Term Storage	+4°C
Long Term Storage	-80°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

PARP2 poly(ADP-ribosyl)ates nuclear factor erythroid 2-related factor 2 (NRF2) affecting NRF2 subcellular localization.: Jankó, L., Tóth, E., et al.; Sci. Rep. 13, 7869 (2023), Application(s): WB / Reactant(s): Mouse, Abstract
Poly(ADP) ribose polymerase promotes DNA polymerase theta-mediated end joining by activation of end resection: Ramsden, D., Feng, W., et al.; Research Square , (2022), Application(s): WB / Reactant(s): Mouse
Silencing of Poly(ADP-Ribose) Polymerase-2 Induces Mitochondrial Reactive Species Production and Mitochondrial Fragmentation.: Kovacs, T., Horváth, I., et al.; Cells 10, (2021), Application(s): WB, Abstract
Silencing of PARP2 Blocks Autophagic Degradation: L. Janko, et al.; Cells 9, 380 (2020), Reactant(s) Mouse, Abstract — Full Text
Poly(ADP-ribose) polymerase-2 Is a Lipid-Modulated Modulator of Muscular Lipid Homeostasis: J. Marton, et al.; Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1863, 1399 (2018), Reactant(s) Mouse, Abstract
Iodinated benzimidazole PARP radiotracer for evaluating PARP1/2 expression in vitro and in vivo: R.C. Anderson, et al.; Nucl. Med. Biol. 43, 752 (2016), Abstract

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Last modified: May 29, 2024

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PARP-2 (mouse) polyclonal antibody

ALX-210-899

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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