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The most sensitive, specific and flexible alternative to more costly and time-consuming methods for oxytocin detection.
- Highly specific ELISA which does not detect vasopressin, providing confidence in assay results
- Ultra-sensitive measurement, detecting as little as 15pg/ml oxytocin
- Cost effective solution, faster and less costly than LC/MS
- Easy-to-use liquid color-coded reagents and pre-coated plates minimizes errors
- Widely published in peer reviewed literature
The Oxytocin EIA kit is a colorimetric competitive enzyme immunoassay kit with results overnight + 1 hour. Absorbance is read at 405 nm. Very low reactivity with vasopressin provides confidence in assay results. Sensitive quantification of 15pg/mL oxytocin. Ready-to-use liquid color-coded reagents reduce errors in the lab.
Oxytocin is a neurohypophysial peptide which is produced in the paraventricular nuclei of the hypothalamus and stored in the posterior pituitary. The molecule consists of nine amino acids linked with a [1-6] disulfide bond and a semi-flexible carboxyamidated tail. A hormone once thought to be limited to female smooth muscle reproductive physiology, more current findings have determined that oxytocin also functions as a neurotransmitter, may be involved in neuropsychiatric disorders, social/sexual behavior, and is important in male reproductive physiology. Oxytocin and the related neurohypophysial peptide, Arg-Vasopressin, maintain renal water and sodium balance.
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Oxytocin ELISA kit Standard curve
Product Details
| Application |
Colorimetric detection, ELISA |
|---|---|
| Application Notes |
For the quantitative determination of Oxytocin in culture supernatants, milk, plasma, and serum from any species. Validated sample types include cerebral spinal fluid, saliva, tissue and urine. |
| Assay Time |
Overnight + 1 hour |
| Compatibility |
This product is compatible with the Absorbance 96 Plate Reader. |
| Contents |
GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution |
| Crossreactivity |
Mesotocin (7%), Oxytocin (100%), Arg8-Vasotocin (7.5%), and <0.02% for other related molecules. |
| Sensitivity |
15pg/ml (range 15.6 – 1,000 pg/ml) |
| Species Reactivity |
Species independent |
| Technical Info / Product Notes |
Cited samples: The Oxytocin ELISA kit has been extensively benchmarked for behavioral studies with plasma samples from a variety of species. Featured in: Frontiers in Neuroscience – Validation of a commercially available enzyme immunoassay for the determination of oxytocin in plasma samples from seven domestic animal species. |
| UniProt ID |
P01178 (human) |
| Wavelength |
405 nm |
Handling & Storage
| Use/Stability |
Store all components at +4°C, except standard and conjugate at -20°C. |
|---|---|
| Shipping |
Blue Ice |
| Regulatory Status |
RUO – Research Use Only |
|---|
- The Effects of Human-Horse Interactions on Oxytocin and Cortisol Levels in Humans and Horses: Y. Jung, et al.; Animals 15, 905 (2025), Abstract
- Oxytocin receptor enhances adipocyte browning and energy metabolism in mice: X. Bao, et al.; Exp. Cell Res. 447, 114534 (2025), Abstract
- Effects of systemic oxytocin administration on ultraviolet B-induced nociceptive hypersensitivity and tactile hyposensitivity in mice: M.D. Boada, et al.; Mol. Pain 20, 17448069241226553 (2024), Abstract
- Control of lipolysis by a population of oxytocinergic sympathetic neurons: Li, E., Wang, L., et al.; Nature 625, 175 (2024), Abstract
- Intestinal microbiome and maternal mental health: preventing parental stress and enhancing resilience in mothers: Matsunaga, M., Takeuchi, M., et al.; Commun. Biol. 7, 235 (2024), Abstract
- Social status predicts physiological and behavioral responses to chronic stress in rhesus monkeys: Zhang, Z., Dong, X., et al.; iScience 27, 110073 (2024), Abstract
- Advances in human oxytocin measurement: challenges and proposed solutions: B.A. Tabak, et al.; Mol. Psychiatry 28, 127 (2023), Abstract
- A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults: E.M.S. Meth, et al.; J. Sleep Res. 32, e13743 (2023), Abstract
- Osmoadaptive GLP-1R signalling in hypothalamic neurones inhibits antidiuretic hormone synthesis and release: M.P. Greenwood, et al.; Mol. Metab. 70, 101692 (2023), Abstract
- Cell-liposome delivery system based on neuroinflammation to target the amygdala for ameliorating depressive-like behaviors: L. Zhou, et al.; Int. J. Pharm. 637, 12272 (2023), Abstract
- Highly Specific Detection of Oxytocin in Saliva: M. Rana, et al.; Int. J. Mol. Sci. 24, 4832 (2023), Abstract
- Medial prefrontal cortex oxytocin mitigates epilepsy and cognitive impairments induced by traumatic brain injury through reducing neuroinflammation in mice: W. Chen, et al.; Sci. Rep. 13, 5214 (2023), Abstract
- Prevalence of burnout and its relation to the neuroendocrine system among pediatric residents during the early Covid-19 pandemic: A pilot feasibility study: D.S. Tawfik, et al.; Compr. Psychoneuroendocrinol. 14, 100174 (2023), Abstract
- Stress during the COVID-19 Pandemic Moderates Pain Perception and Momentary Oxytocin Levels: E. Schneider, et al.; J. Clin. Med. 12, 2333 (2023), Abstract
- The influence of manual semen collection in male trained dogs (Canis familiaris), in the presence or absence of a female in estrus, on the concentrations of cortisol, oxytocin, prolactin and testosterone: M. Woszczyło, et al.; PLoS One 18, e0278524 (2023), Abstract
- Impact of IDO activation and alterations in the kynurenine pathway on hyperserotonemia, NAD+ production, and AhR activation in autism spectrum disorder: J.M. Launay, et al.; Transl. Psychiatry 13, 380 (2023), Abstract
- Intranasal Oxytocin and Pain Reduction: Testing a Social Cognitive Mediation Model: P. Long, et al.; Brain Sci. 13, 1689 (2023), Abstract
- Serum Oxytocin, Cortisol and Social Behavior in Calves: A Study in the Impossible Task Paradigm: C. Pinelli, et al.; Animals (Basel) 13, 646 (2023), Application(s): Bovine serum, Abstract — Full Text
- Oxytocin levels and self-reported anxiety during interactions between humans and cows: B. Berget, et al.; Front. Psychol. 14, 1252463 (2023), Application(s): Human plasma, Abstract — Full Text
- The Mood, Mother and Child Study: Protocol for a Prospective Longitudinal Study and Randomized Controlled Trial: W.R. Mills-Koonce, et al.; JMIR Res. Protoc. 12, e51132 (2023), Abstract
- Development of the Paternal Brain in Humans throughout Pregnancy: Diaz-Rojas, F., Matsunaga, M., et al.; J. Cogn. Neurosci. 35, 396 (2023), Abstract
- Exogenous Oxytocin Administration Restores Memory in Female APP/PS1 Mice: Koulousakis, P., Willems, E., et al.; J. Alzheimers Dis. 96, 1207 (2023), Abstract
- Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling: Danhof, H. A., Lee, J., et al.; Gut Microbes 15, 2256043 (2023), Abstract
- The association between neuropeptide oxytocin and neuropsychiatric disorders after orthopedic surgery stress in older patients: Dong, W., Ding, Z., et al.; BMC Geriatr. 23, 416 (2023), Abstract
- Oxytocin changes in women with emergency cesarean section: Association with maternal blues by delivery mode: E. Shishido & S. Horiuchi; Heliyon 9, e15405 (2023), Abstract — Full Text
- Excessive follicle-stimulating hormone during ovarian stimulation of cattle may induce premature luteinization of most ovulatory-size follicles: Z.L. Clark, et al.; Biol. Reprod. , (2022), Abstract
- Oral Supplementation with L-Carnosine Attenuates Social Recognition Deficits in CD157KO Mice via Oxytocin Release: T. Tsuji, et al.; Nutrients 14, 803 (2022), Abstract
- Association between salivary oxytocin levels and the amygdala and hippocampal volumes: Q. Shou, et al.; Brain Struct. Funct. 227, 2503 (2022), Abstract
- Evaluating the neuropeptide-social cognition link in ageing: the mediating role of basic cognitive skills: R. Polk, et al.; Philos. Trans. R. Soc. Lond. B Biol. Sci. 29, 377 (2022), Abstract
- Altered hormonal patterns in borderline personality disorder mother-child interactions: J. Bonfig, et al.; Psychoneuroendocrinology 143, 105822 (2022), Abstract
- Utility of Downstream Biomarkers to Assess and Optimize Intranasal Delivery of Oxytocin: M. DuBois, et al.; Pharmaceutics 14, 1178 (2022), Abstract
- Early Postpartum Maternal and Newborn Responses to Auditory, Tactile, Visual, Vestibular, and Olfactory Stimuli: R.W. Traut, et al.; J. Obstet. Gynecol. Neonatal Nurs. 51, 402 (2022), Abstract
- Identification of oxytocin expression in human and murine microglia: Y. Maejima, et al.; Prog. Neuropsychopharmacol. Biol. Psychiatry 119, 110600 (2022), Abstract
- Improvement of several stress response and sleep quality hormones in men and women after sleeping in a bed that protects against electromagnetic fields: E.D.D. Cerro, et al.; Environ. Health 21, 72 (2022), Abstract
- Correlations between behavior and hormone concentrations or gut microbiome imply that domestic cats (Felis silvestris catus) living in a group are not like ‘groupmates’: H. Koyasu, et al.; PLoS One 17, e0269589 (2022), Abstract
- Is oxytocin a trust hormone? Salivary oxytocin is associated with caution but not with general trust: Q. Shou, et al.; PLoS One 17, e0267988 (2022), Abstract
- Oxytocin modulates sensitivity to acculturation and discrimination stress in pregnancy: A.C. Incollingo Rodriguez, et al.; Psychoneuroendocrinology 141, 105769 (2022), Abstract
- Transcription factor Creb3l1 maintains proteostasis in neuroendocrine cells: M. Greenwood, et al.; Mol. Metab. 63, 101542 (2022), Abstract
- Infant Stimulation Induced a Rapid Increase in Maternal Salivary Oxytocin: K. Minami, et al.; Brain Sci. 12, 1246 (2022), Abstract
- Chronic social stress during early development is involved in antisocial maltreatment behavior in mice: D. Jeon, et al.; Encephalitis 2, 98 (2022), Abstract
- Sociality of Cats toward Humans Can Be Influenced by Hormonal and Socio-Environmental Factors: Pilot Study: H. Koyasu, et al.; Animals (Basel) 13, 146 (2022), Application(s): Cat urine, Abstract — Full Text
- Serum Oxytocin in Cows Is Positively Correlated with Caregiver Interactions in the Impossible Task Paradigm: B. D’Aniello, et al.; Animals (Basel) 13, 276 (2022), Application(s): Bovine serum, Abstract — Full Text
- Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71: Kozlova, E. V., Valdez, M. C., et al.; Arch. Toxicol. 96, 335 (2022), Abstract
- What are oxytocin assays measuring? Epitope mapping, metabolites, and comparisons of wildtype & knockout mouse urine: Gnanadesikan, G. E., Hammock, E. A. D., et al.; Psychoneuroendocrinology 143, 105827 (2022), Abstract
- Pain relief associated with decreased oxyhemoglobin level in left dorsolateral prefrontal cortex: S. Miyashiro, et al.; PLoS One 16, e0256626 (2021), Application(s): ELISA using human saliva, Abstract — Full Text
- An improved sample extraction method reveals that plasma receptor for advanced glycation end-products (RAGE) modulates circulating free oxytocin in mice: S.M. Cherepanov, et al.; Peptides 146, 170649 (2021), Abstract
- Hormonal and Neurological Aspects of Dog Walking for Dog Owners and Pet Dogs: J. Akiyama & M. Ohta; Animals 11, 2732 (2021), Abstract
- Oxytocin levels in response to pituitary provocation tests in healthy volunteers: C.O. Sailer, et al.; Eur. J. Endocrinol. 185, 355 (2021), Application(s): ELISA using human plasma, Abstract
- Oxytocin in young children with Prader-Willi syndrome: Results of a randomized, double-blind, placebo-controlled, crossover trial investigating 3 months of oxytocin: L. Damen, et al.; Clin. Endocrinol. 94, 774 (2021), Application(s): ELISA using human plasma, Abstract — Full Text
- OXTR-Related Markers in Clinical Depression: a Longitudinal Case–Control Psychotherapy Study: I.C. Reiner, et al.; J. Mol. Neurosci. , (2021), Abstract
- Enhancement of oxytocin in the medial prefrontal cortex reverses behavioral deficits induced by repeated ketamine administration in mice: W. Zhu, et al.; Front. Neurosci. 15, 723064 (2021), Application(s): ELISA using mouse plasma, Abstract — Full Text
- Effects of playing Angklung and practicing silence on emotion, cognition and oxytocin levels in children: a preliminary study: M.M. Maramis, et al.; Maays. J. Med. Sci. 28, 105 (2021), Application(s): ELISA using human saliva, Abstract — Full Text
- Beta-Carotene derivatives as novel therapy for the prevention and treatment of autistic symptoms: Y. Avraham, et al.; Bioorg. Chem. 115, 105224 (2021), Application(s): ELISA using mouse serum, Abstract
- Storytelling increases oxytocin and positive emotions and decreases cortisol and pain in hospitalized children: G. Brockington, et al.; PNAS 118, e2018409118 (2021), Application(s): ELISA using human saliva, Abstract — Full Text
- Oxytocin in the anterior cingulate cortex attenuates neuropathic pain and emotional anxiety by inhibiting presynaptic long-term potentiation: X. H. Li, et al.; Cell Rep. 36, 109411 (2021), Abstract
- Autism-associated biomarkers: test–retest reliability and relationship to quantitative social trait variation in rhesus monkeys: O. Oztan, et al.; Mol. Autism 12, 13229 (2021), Abstract
- CAPS2 deficiency impairs the release of the social peptide, oxytocin, as well as oxytocin-associated social behavior: S. Fujima, et al.; J. Neurosci. 1523, 3240 (2021), Abstract
- The Mechanism of the Solute-Free Water Reabsorption Increase in the Rat Kidney by Oxytocin Saluresis: Y.V. Natochin, et al.; Dokl Biochem Biophys 497, 190 (2021), Abstract
- Specificity of plasma oxytocin immunoassays: A comparison of commercial assays and sample preparation techniques using oxytocin knockout and wildtype mice: G.E. Gnanadesikan, et al.; Psychoneuroendocrinology 132, 105368 (2021), Application(s): Unextracted and extracted mouse plasma, Abstract
- Oxytocin, cortisol, and cognitive control during acute and naturalistic stress: S.Y. Kuchenbecker, et al.; Stress 24, 370 (2021), Abstract
- “Live together, die alone”: The effect of re-socialization on behavioural performance and social-affective brain-related proteins after a long-term chronic social isolation stress: D. Rivera, et al.; Neurobiol. Stress 14, 100289 (2021), Abstract
- Validation of a newly generated oxytocin antibody for enzyme-linked immunosorbent assays: K. Murata, et al.; J. Vet. Med. Sci. 83, 478 (2021), Abstract — Full Text
- Exploring women’s oxytocin responses to interactions with their pet cats: E.A. Johnson, et al.; PeerJ 9, e12393 (2021), Application(s): Human saliva, Abstract — Full Text
- Analytical and physiological validation of an enzyme immunoassay to measure oxytocin in dog, wolf, and human urine samples: G. Wirobski, et al.; Sci. Rep. 11, 12793 (2021), Application(s): Dog, Wolf, and human urine, Abstract — Full Text
- Minimally invasive biomarkers to detect maternal physiological status in sow saliva and milk: S.A. Hall, et al.; Animal 15, 100369 (2021), Abstract
- Development of the paternal brain in expectant fathers during early pregnancy: Díaz-Rojas, F., Matsunaga, M., et al.; Neuroimage 225, 117527 (2021), Abstract
- Persistent autism-relevant phenotype produced by i>in utero/i> and lactational exposure of female mice to the commercial PBDE mixture, DE-71: Kozlova, E. V., Valdez, M. C., et al.; bioRxiv , (2021)
- Changes in the cortisol and oxytocin levels of first-time pregnant women during interaction with an infant: a randomized controlled trial: N. Sonoda, et al.; BMC Pregnancy Childbirth 21, 162 (2021), Sample Type: Human Saliva, Abstract — Full Text
- Dysregulation of oxytocin and dopamine in the corticostriatal circuitry in bipolar II disorder: S. Wei, et al.; Transl. Psychiatry 10, 281 (2020), Abstract — Full Text
- Breastfeeding Dynamically Changes Endogenous Oxytocin Levels and Emotion Recognition in Mothers: M. Matsunaga, et al.; Biol. Lett. 16, 20200139 (2020), Abstract — Full Text
- Neonatal CSF vasopressin concentration predicts later medical record diagnoses of autism spectrum disorder: O. Oztan, et al.; PNAS 117, 10609 (2020), Abstract — Full Text
- Maternal responsivity and oxytocin in opioid-dependent mothers: K.M. Daigle, et al.; Dev. Psychobiol. 62, 21 (2020), Abstract
- Interference of Asfotase Alfa in Immunoassays Employing Alkaline Phosphatase Technology: I. D. Piec, et al.; J. Appl. Lab. Med. 5, 290 (2020), Application(s): Human urine and plasma, Abstract
- Prenatal exposure to the probiotic Lactococcus lactis decreases anxiety-like behavior and modulates cortical cytoarchitecture in a sex specific manner: Surzenko, N., Pjetri, E., et al.; PLoS One 15, e0223395 (2020), Abstract
- Changes in salivary oxytocin levels and bonding disorder in women from late pregnancy to early postpartum: A pilot study: E. Shishido, et al.; PLoS One 14, e0221821 (2019), Abstract
- Oxytocin reactivity to an emotional challenge paradigm and its relation to social-cognitive functions in healthy volunteers: N. Kampka, et al.; J. Neural. Transm. (Vienna) 126, 211 (2019), Application(s): ELISA using human plasma, Abstract
- Nanoparticle encapsulation increases the brain penetrance and duration of action of intranasal oxytocin: A. Oppong-Damoah, et al.; Horm. Behav. 108, 20 (2019), Application(s): ELISA using mouse CSF and plasma, Abstract
- Maternal nicotinamide riboside enhances postpartum weight loss, juvenile offspring development, and neurogenesis of adult offspring: P.H. Ear, et al.; Cell Rep. 26, 969 (2019), Application(s): ELISA using mouse and rat plasma samples, Abstract
- Different oxytocin responses to acute methamphetamine treatment in juvenile female rats perinatally exposed to stress and/or methamphetamine administration: A. Holubova, et al.; Front. Physiol. 10, 305 (2019), Application(s): ELISA using rat plasma, Abstract — Full Text
- ERP study on the associations of peripheral oxytocin and prolactin with inhibitory processes involving emotional distraction: S. Hayashi, et al.; J. Physiol. Anthropol. 38, 5 (2019), Abstract — Full Text
- Analytical validation of an Enzyme Immunoassay for the measurement of urinary oxytocin in dogs and wolves: F.S. Schaebs, et al.; Gen. Comp. Endocrinol. 281, 73 (2019), Application(s): Extensive validation using canine urine, Abstract
- The role of oxytocin in early mother-infant interactions: Variations in maternal affect attunement: G. Markova & B. Siposova; Infant Behav. Dev. 55, 58 (2019), Abstract
- Plasma oxytocin and vasopressin levels in young and older men and women: Functional relationships with attachment and cognition: G. Plasencia, et al.; Psychoneuroendocrinology 110, 104419 (2019), Abstract
- Oxytocin, vasopressin and trust: Associations with aggressive behavior in healthy young males: Y.R. Berends, et al.; Physiol. Behav. 204, 180 (2019), Abstract
- Hyperprolactinemic African elephant (Loxodonta africana) females exhibit elevated dopamine, oxytocin and serotonin concentrations compared to normal cycling and noncycling, low prolactin elephants: N. A Prado, et al.; Biol. Reprod. 100, 1549 (2019), Abstract
- High oxytocin infants gain more mass with no additional maternal energetic costs in wild grey seals (Halichoerus grypus): K.J. Robinson, et al.; Psychoneuroendocrinology 110, 104423 (2019), Abstract
- Effects of Environmental Enrichment in Maternally Separated Rats: Age and Sex-Specific Outcomes: R. Doreste, et al.; Front. Behav. Neurosci. 13, 198 (2019), Abstract
- Effects of Camellia Sinensis Extract on Repeated Restraint Stress-Induced Ovariectomized Female Rats: M. Ye, et al.; BioMed Res. Int. 2019, 1926352 (2019), Abstract
- Daily oxytocin patterns in relation to psychopathy and childhood trauma in residential youth: I. Fragkaki, et al.; Psychoneuroendocrinology 102, 105 (2019), Abstract
- Circulating Oxytocin Is Genetically Determined and Associated With Obesity and Impaired Glucose Tolerance: M.F.J. Weingarten, et al.; J. Clin. Endocrinol. Metab. 104, 5621 (2019), Abstract
- Circulating levels of oxytocin may be elevated in complicated grief: a pilot study: E. Bui, et al.; Eur. J. Psychotraumatol. 10, 1646603 (2019), Abstract
- Child’s oxytocin response to mother-child interaction: The contribution of child genetics and maternal behavior: R. Baião, et al.; Psychoneuroendocrinology 102, 79 (2019), Abstract
- Amygdala–Hippocampal Connectivity Is Associated With Endogenous Levels of Oxytocin and Can Be Altered by Exogenously Administered Oxytocin in Adults With Autism: K. Alaerts, et al.; Biol. Psychiatry 4, 655 (2019), Abstract
- Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice: Y. Yamamoto, et al.; Commun. Biol. 2, 76 (2019), Application(s): Mouse serum and cerebrospinal fluid, Abstract — Full Text
- The Role of Oxytocin in the Dog–Owner Relationship: S. Marshall-Pescini, et al.; Animals (Basel) 9, 792 (2019), Application(s): Dog and human urine, Abstract — Full Text
- Osmolyte Depletion and Thirst Suppression Allow Hibernators to Survive for Months without Water: Feng, N. Y., Junkins, M. S., et al.; Curr. Biol. 29, 3053 (2019), Abstract
- Prenatal exposure to the probiotic i>Lactococcus lactis/i> decreases anxiety-like behavior and modulates cortical cytoarchitecture in a sex specific manner: Surzenko, N., Pjetri, E., et al.; bioRxiv , (2019)
- The Effects of Equine Assisted Therapy on Plasma Cortisol and Oxytocin Concentrations and Heart Rate Variability in Horses and Measures of Symptoms of Post-Traumatic Stress Disorder in Veterans: K. Malinkowski, et al.; J. Equine Vet. Sci. 64, 17 (2018), Application(s): Horse plasma, Abstract
- Facial expression and oxytocin as possible markers of positive emotions in horses: L. Lansade, et al.; Sci. Rep. 8, 14680 (2018), Application(s): Extracted horse blood, Abstract — Full Text
- Validation of salivary oxytocin and vasopressin as biomarkers in domestic dogs: E.L. MacLean, et al.; J. Neurosci. Methods 293, 67 (2018), Application(s): ELISA using dog saliva, Abstract
- Is the serum oxytocin level altered by treatment in rheumatoid arthritis patients complicated with depression?: Y. Miwa, et al.; Eur. J. Rheumatol. 5, 22 (2018), Application(s): ELISA using human serum, Abstract — Full Text
- Intranasal oxytocin attenuates reactive and ongoing, chronic pain in a model of mild traumatic brain injury: A.C. Meidahl, et al.; Headache 58, 545 (2018), Application(s): ELISA using a variety of rat tissues, Abstract
- Imaging correlates of behavioral impairments: An experimental PET study in the rat pilocarpine epilepsy model: V. Di Liberto, et al.; Neurobiol. Dis. 118, 9 (2018), Application(s): ELISA using rat serum, Abstract
- Gut microbiota varies by opioid use, circulating leptin and oxytocin in African American men with diabetes and high burden of chronic disease: E. Barengolts, et al.; PLoS One 13, e0194171 (2018), Application(s): Human urine, Abstract — Full Text
- Variable oxytocin levels in humans with different degrees of obesity and impact of gastric bypass surgery: Z. Pataky, et al.; Int. J. Obes. 43, 1120 (2018), Abstract
- Effects of breast stimulation for spontaneous onset of labor on salivary oxytocin levels in low-risk pregnant women: A feasibility study: K. Takahata, et al.; PLoS One 13, e0192757 (2018), Abstract — Full Text
- BDNF levels are associated with autistic traits in the general population: N. Brondino, et al.; Psychoneuroendocrinology 89, 131 (2018), Application(s): Blood Samples, Abstract
- Providing straw to allow exploratory behaviour in a pig experimental system does not modify putative indicators of positive welfare: peripheral oxytocin and serotonin: M. Marcet Rius, et al.; Animal 12, 2138 (2018), Application(s): Serotonin levels in pig plasma, Abstract
- Oxytocin is lower in African American men with diabetes and associates with psycho-social and metabolic health factors: Y. Eisenberg, et al.; PLoS One. 13, e0190301 (2018), Application(s): Oxytocin levels in human urine, Abstract
- Nanoparticle formulations that allow for sustained delivery and brain targeting of the neuropeptide oxytocin: Zaman, R. U., Mulla, N. S., et al.; Int. J. Pharm. 548, 698 (2018), Abstract
- Orexin action on oxytocin neurons in the paraventricular nucleus of the hypothalamus: Y. Maejima, et al.; Neuroreport 28, 360 (2017), Application(s): Rat cells supernatant, Abstract
- A comparison of methods to measure central and peripheral oxytocin concentrations in human and non-human primates: A. Lefevre, et al.; Sci. Rep. 7, 17222 (2017), Application(s): Oxytocin in CSF and plasma in humans and primates, Abstract — Full Text
- Biomarker discovery for disease status and symptom severity in children with autism: O. Oztan, et al.; Psychoneuroendocrinology 89, 39 (2017), Abstract
- Oxytocin and Cortisol Levels in Dog Owners and Their Dogs Are Associated with Behavioral Patterns: An Exploratory Study: M. Petersson, et al.; Front. Psychol. 8, 1796 (2017), Application(s): Dog plasma, Abstract — Full Text
- Oxytocin and Social Bonds: The Role of Oxytocin in Perceptions of Romantic Partners’ Bonding Behavior: S.B. Algoe, et al.; Psychol. Sci. 28, 1763 (2017), Application(s): Human urine samples, Abstract — Full Text
- A statistical method to calculate blood contamination in the measurement of salivary hormones in healthy women: G.A. Behr, et al.; Clin. Biochem. 50, 436 (2017), Application(s): Serum and salivary hormonal levels were determined, Abstract
- Sex differences in associations of arginine vasopressin and oxytocin with resting-state functional brain connectivity: L.H. Rubin, et al.; J. Neurosci. Res. 95, 576 (2017), Application(s): Human serum samples, Abstract — Full Text
- Increase in salivary oxytocin and decrease in salivary cortisol after listening to relaxing slow-tempo and exciting fast-tempo music: Y. Ooishi, et al.; PLoS One 12, e0189075 (2017), Application(s): Human saliva, Abstract — Full Text
- Intergenerational accumulation of impairments in maternal behavior following postnatal social stress: B.C. Nephew, et al.; Psychoneuroendocrinology 82, 98 (2017), Application(s): Rat serum, Abstract — Full Text
- Intestinal transepithelial permeability of oxytocin into the blood is dependent on the receptor for advanced glycation end products in mice: H. Higashida, et al.; Sci. Rep. 7, 7883 (2017), Application(s): Mouse plasma and culture serum supernatant, Abstract — Full Text
- Validation of a Commercially Available Enzyme ImmunoAssay for the Determination of Oxytocin in Plasma Samples from Seven Domestic Animal Species: C. Bienboire-Frosini, et al.; Front. Neurosci. 11, 524 (2017), Application(s): Cat, Dog, Horse, Pig, Goat, Sheep, and Cow plasma, Abstract — Full Text
- The regulation of oxytocin and oxytocin receptor in human placenta according to gestational age: Kim, S. C., Lee, J. E., et al.; J. Mol. Endocrinol. 59, 235 (2017), Abstract
- Chronic Methamphetamine Self-Administration Dysregulates Oxytocin Plasma Levels and Oxytocin Receptor Fibre Density in the Nucleus Accumbens Core and Subthalamic Nucleus of the Rat: S.J. Baracz, et al.; J. Neuroendocrinol. 28, (2016), Application(s): Rat plasma, Abstract
- A Novel Mutant Allele of Pw1/Peg3 Does Not Affect Maternal Behavior or Nursing Behavior: A.L. Denizot, et al.; PLoS Genet. 12, e1006053 (2016), Application(s): OT concentration mouse plasma, Abstract — Full Text
- Opposite effects of central oxytocin and arginine vasopressin on changes in gastric motor function induced by chronic stress: M. Bülbül, et al.; Peptides 87, 1 (2016), Application(s): Determination of Oxytocin concentrations in microdialysates, Abstract
- Can hypoxia enhance sexual arousal?-Molecular-biological analysis of the hypothalamus in male rats placed with oestrous female rats under hypoxic conditions-: H. Inoue, et al.; Int. J. Clin. Exp. Med. 9, 19512 (2016), Application(s): Serum oxytoxin, Full Text
- Serotonin 1A agonism decreases affiliative behavior in pair-bonded titi monkeys: R.H. Horm, et al.; Horm. Behav. 86, 71 (2016), Application(s): Blood sampling and hormone analysis, titi monkey plasma, Abstract
- Neonatal interventions differently affect maternal care quality and have sexually dimorphic developmental effects on corticosterone secretion: N.S. Couto-Pereira, et al.; Int. J. Dev. Neurosci. 55, 72 (2016), Application(s): Oxytocin assay, rats, Abstract
- Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial: H. Kosaka, et al.; Transl. Psychiatry 6, e872 (2016), Application(s): Quantifying plasma oxytocin levels, Abstract — Full Text
- Plasma Oxytocin in Children with Autism and Its Correlations with Behavioral Parameters in Children and Parents: V.M. Husarova, et al.; Psychiatry Investig. 13, 174 (2016), Application(s): Plasma oxytocin measurement, Abstract — Full Text
- A Cohort Study of the Level of Plasma Oxytocin associated with Autism Spectrum Disorder in Japanese Males, Females and Pregnant Females: Y. Sano, et al.; Clin. Med. Biochemistry 2, 113 (2016), Application(s): Oxytocin levels were measured in human plasma samples, Full Text
- Oxytocin Secretion in Healthy Men: C. Baskaran, et al.; Endocr. Rev. , (2016), Application(s): Human serum oxytocin levels were measured, Full Text
- Comparing oxytocin and cortisol regulation in a double-blind, placebo-controlled, hydrocortisone challenge pilot study in children with autism and typical development: B.A. Corbett, et al.; J. Neurodev. Disord. 8, 32 (2016), Application(s): Oxytocin assay, human samples, Abstract — Full Text
- Increased Serum Levels of Oxytocin in ‘Treatment Resistant Depression in Adolescents (TRDIA)’ Group: T. Sasaki, et al.; PLoS One 11, e0160767 (2016), Application(s): Measurement of oxytocin levels from serum, Abstract — Full Text
- Oxytocin promotes functional coupling between paraventricular nucleus and both sympathetic and parasympathetic cardioregulatory nuclei: J.R. Yee, et al.; Horm. Behav. 80, 82 (2016), Application(s): Hormone measurement in whole blood samples, Abstract
- Oxytocin is associated with infant-care behavior and motivation in cooperatively breeding marmoset monkeys: C. Finkenwirth, et al.; Horm. Behav. 80, 10 (2016), Application(s): Oxytocin levels were measured in monkeys, Abstract
- Evaluation of an antenatal acupuncture intervention as an adjunct therapy for antenatal depression (AcuAnteDep): study protocol for a pragmatic randomised controlled trial: S.M. Ornsby, et al.; Trials 17, 93 (2016), Application(s): Oxytocin levels were measured in saliva samples, Abstract — Full Text
- Plasma and CSF oxytocin levels after intranasal and intravenous oxytocin in awake macaques: S.M. Freeman, et al.; Psychoneuroendocrinology 66, 185 (2016), Application(s): Measured levels of OT in plasma and CSF, Abstract
- Measuring Oxytocin and Vasopressin: Bioassays, Immunoassays and Random Numbers: G. Leng, et al.; J. Neuroendocrinol. 28, 10 (2016), Application(s): Review on plasma extraction, Abstract
- Effects of positive and negative human contacts and intranasal oxytocin on cerebrospinal fluid oxytocin: J.-L. Rault; Psychoneuroendocrinology 69, 60 (2016), Application(s): Pig Cerebrospinal Fluid, Abstract
- Validity of physiological biomarkers for maternal behavior in cows – A comparison of beef and dairy cattle: K. Geburt, et al.; Physiol. Behav. 139, 361 (2015), Application(s): OT concentration in cow saliva samples, Abstract
- Salivary oxytocin in clinically anxious youth: Associations with separation anxiety and family accommodation: E.R. Lebowitz, et al.; Psychoneuroendocrinology 65, 35 (2015), Application(s): Levels of oxytocin in human saliva, Abstract
- Oxytocin affects spontaneous neural oscillations in trauma-exposed war veterans: M. Eidelman-Rothman, et al.; Front. Behav. Neurosci. 9, 165 (2015), Application(s): Levels of oxytocin in human plasma, Abstract — Full Text
- Explicit and implicit caregiving interests in expectant fathers: Do endogenous and exogenous oxytocin and vasopressin matter?: C.C. Cohen-Bendahan, et al.; Infant Behav. Dev. 41, 26 (2015), Application(s): Levels of oxytocin in human urine, Abstract
- Effect of long-term intranasal oxytocin on sexual dysfunction in premenopausal and postmenopausal women: a randomized trial: D.A. Muin, et al.; Fertil. Steril. 104, 715 (2015), Application(s): Levels of oxytocin in human plasma, Abstract
- Central corticosterone disrupts behavioral and neuroendocrine responses during lactation: A.S. Pereira, et al.; Neurosci. Lett. 606, 88 (2015), Application(s): Levels of oxytocin in rat plasma, Abstract
- Association between blood level of plasma oxytocin and novelty seeking among methadone-maintained heroin users: S.H. Lin, et al.; Neuropsychobiology 71, 65 (2015), Application(s): Levels of oxytocin in human plasma, Abstract
- A sexually dimorphic hypothalamic circuit controls maternal care and oxytocin secretion: N. Scott, et al.; Nature 525, 519 (2015), Application(s): ELISA using isoflurane and blood samples from mice, Abstract
- Strongly bonded family members in common marmosets show synchronized fluctuations in oxytocin: C. Finkenwirth, et al.; Physiol. Behav. 151, 246 (2015), Application(s): ELISA using marmoset urine, Abstract
- Electro-acupuncture improves the social interaction behavior of rats: H.F. Zhang, et al.; Physiol. Behav. 151, 485 (2015), Application(s): ELISA using rat brain tissue, Abstract
- Conspecific recognition and aggression reduction to familiars in newly weaned, socially plastic mammals: K.J. Robinson, et al.; Behav. Ecol. Sociobiol. 59, 1383 (2015), Application(s): ELISA using seal pup plasma, Abstract — Full Text
- Salivary oxytocin concentrations in seven boys with autism spectrum disorder received massage from their mothers: a pilot study: S. Tsuji, et al.; Front. Psychiatry 6, 58 (2015), Application(s): ELISA using human saliva, Abstract
- Salivary oxytocin increases concurrently with testosterone and time away from home among returning Tsimane’ hunters: A.V. Jaeggi, et al.; Biol. Lett. 11, 20150058 (2015), Application(s): ELISA using human saliva, Abstract — Full Text
- Oxytocin-induced coping with stressful life events in old age depends on attachment; findings from the cross-sectional KORA Age Study: R.T. Emeny, et al.; Psychoneuroendocrinology 56, 132 (2015), Application(s): ELISA using human plasma, Abstract
- Oxytocin increases VTA activation to infant and sexual stimuli in nulliparous and postpartum women: R. Gregory, et al.; Horm. Behav. 69, 82 (2015), Application(s): ELISA using human urine, Abstract
- Myometrial contractility influences oxytocin receptor (OXTR) expression in term trophoblast cells obtained from the maternal surface of the human placenta: Szukiewicz, D., Bilska, A., et al.; BMC Pregnancy Childbirth 15, 220 (2015), Abstract
- Breaking bonds in male prairie vole: long-term effects on emotional and social behavior, physiology, and neurochemistry: P. Sun, et al.; Brain Behav. Immun. 15, 265 (2014), Application(s): EIA using prairie vole plasma samples, Abstract
- Oxytocin administration attenuates atherosclerosis and inflammation in Watanabe Heritable Hyperlipidemic rabbits: A. Szeto, et al.; Psychopharmacol. 38, 685 (2013), Application(s): Oxytocin in plasma was measured, Abstract — Full Text
- Oxytocin increases the influence of public service advertisements: P.Y. Lin, et al.; PLoS One 8, e56934 (2013), Abstract
- Effects of early life social stress on endocrinology, maternal behavior, and lactation in rats: L.M. Carini, et al.; Horm. Behav. 64, 634 (2013), Application(s): EIA using rat plasma, Abstract
- Neonatal CSF oxytocin levels are associated with parent report of infant soothability and sociability: C.L. Clark, et al.; Psychoneuroendocrinology 38, 1208 (2013), Application(s): ELISA using human cerebral spinal fluid., Abstract
- Peripheral vasopressin but not oxytocin relates to severity of acute psychosis in women with acutely-ill untreated first-episode psychosis: L.H. Rubin, et al.; Schizophr. Res. 146, 138 (2013), Application(s): ELISA using human serum., Abstract
- Validation of a new multiplex assay against individual immunoassays for the quantification of reproductive, stress, and energetic metabolism biomarkers in urine: K.G. Salvante, et al.; Am. J. Hum. Biol. 24, 81 (2012), Application(s): EIA using human urine, Abstract — Full Text
- Peripheral oxytocin in female baboons relates to estrous state and maintenance of sexual consortships: L.R. Moscovice, et al.; Horm. Behav. 62, 592 (2012), Application(s): ELISA using baboon urine, Abstract
- Oxytocin and vasopressin are dysregulated in Williams Syndrome, a genetic disorder affecting social behavior: L. Dai, et al.; PLoS One 7, e38513 (2012), Application(s): ELISA using human serum, Abstract — Full Text
- Hormone concentration changes temporally associated with the hour of transition from preluteolysis to luteolysis in mares: O.J. Ginther & M.A. Beg; Anim. Reprod. Sci. 129, 67 (2011), Application(s): Horse plasma, Abstract
- Evaluation of Enzyme Immunoassay and Radioimmunoassay Methods for the Measurement of Plasma Oxytocin: A. Szeto, et al.; Psychosomatic Medicine 73, 393 (2011), Application(s): Oxytocin was measured in extracted and unextracted human plasma samples, Abstract
- Reproductive experience affects parental retrieval behaviour associated with increased plasma oxytocin levels in wild-type and CD38-knockout mice: O. Lopatina, et al.; J. Neuroendocrinol. 23, 1125 (2011), Application(s): Plasma oxytocin levels in mice, Abstract
- Genistein alters the release of oxytocin, prostaglandins, cortisol and LH during insemination in gilts: M. Norrby, et al.; Reprod. Domest. Anim. 46, 316 (2011), Application(s): ELISA using pig plasma, Abstract
- Estradiol effects on behavior and serum oxytocin are modified by social status and polymorphisms in the serotonin transporter gene in female rhesus monkeys: V. Michopoulos, et al.; Horm. Behav. 59, 528 (2011), Application(s): ELISA using rhesus monkey serum, Abstract
- The cross-generation transmission of oxytocin in humans: R. Feldman, et al.; Hormones and Behavior 58, 669 (2010), Application(s): EIA using human saliva, Abstract
- Mothers’ and Children’s Concentrations of Oxytocin Following Close, Physical Interactions with Biological and Non-biological Children: J. Bick & M. Dozier; Dev. Psychobiol. 52, 100 (2010), Application(s): Concentration in urine, Abstract — Full Text
- Variation in oxytocin is related to variation in affiliative behavior in monogamous, pairbonded tamarins: C.T. Snowdon, et al.; Horm. Behav. 58, 614 (2010), Application(s): ELISA using tamarin urine, Abstract
- Calcium, parathyroid hormone, oxytocin and pH profiles in the whelping bitch: F.K. Hollinshead, et al.; Theriogenology 73, 1276 (2010), Application(s): ELISA using dog serum, Abstract
- Prolactin promotes oxytocin and vasopressin release by activating neuronal nitric oxide synthase in the supraoptic and paraventricular nuclei: C. Vega, et al.; Am. J. Physiol. Regul. Integr. Comp. Physiol. 299, R1701 (2010), Application(s): ELISA using rat plasma, Abstract — Full Text
- Effects of naltrexone on cortisol levels in heavy drinkers: L.A. Ray, et al.; Pharmacol. Biochem. Behav. 91, 489 (2009), Application(s): EIA using human saliva, Abstract
- PVN electrical stimulation prolongs withdrawal latencies and releases oxytocin in cerebrospinal fluid, plasma, and spinal cord tissue inintact and neuropathic rats: M. Condes-Lara, et al.; Pain 140, 265 (2008), Application(s): EIA using rat cerbrospinal fluid, plasma and tissue, Abstract
- Influence of a ‘Warm Touch’ Support Enhancement Intervention Among Married Couples on Ambulatory Blood Pressure, Oxytocin, Alpha Amylase,and Cortisol: J. Holt-Lunstad, et al.; Psychosom. Med. 70, 976 (2008), Application(s): EIA using human plasma and saliva, Abstract
- Monetary sacrifice among strangers is mediated by endogenous oxytocin release after physical contact: P. Zak, et al.; Evol. Hum. Behav. 29, 375 (2008), Application(s): EIA using human plasma and serum.
- Oxytocin in the circadian timing of birth: J. Roizen, et al.; PLoS One 2, e922 (2007), Application(s): EIA using mouse plasma, Abstract — Full Text
- Tachykinin NK3 receptor contribution to systemic release of vasopressin and oxytocin in response to osmotic and hypotensive challenge: G.E. Haley, et al.; Am. J. Physiol. Regul. Integr. Comp. Physiol. 293, R931 (2007), Sample Type: Rat Plasma, Abstract — Full Text
- Hormonal correlates of human paternal interactions: A hospital-based investigation in urban Jamaica: P.B. Gray, et al.; Horm. Behav. 52, 499 (2007), Sample Type: Human Urine, Abstract
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