OxiSelect™ Nitrotyrosine ELISA Kit (5 plates)

• Sensitive detection of 3-Nitrotyrosine as low as 10 nM
• Suitable for use with cell lysates, serum, plasma and purified proteins
• Nitrated BSA provided as positive control

Nitric oxide influences a variety of biological processes including cell proliferation, apoptosis, neurotoxicity and extracellular matrix remodeling. Nitric oxide reacts with superoxide to form peroxynitrite, which in turn nitrates tyrosine residues in proteins. Nitrotyrosine therefore serves as a marker for peroxynitrite action in a variety of disease states and in conditions of cellular damage and oxidative stress. Our OxiSelect™ Nitrotyrosine ELISA Kit provides a sensitive method to measure the formation of 3-nitrotyrosine in proteins.