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Oxaliplatin

ALX-400-042

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Antitumor agent

Platinum analog which has wide spectrum anticancer activity. It is found to be more active against human melanoma cell lines, and has better biochemical, pharmacological and cytotoxic properties than cisplatin and carboplatin.

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Product Details

Appearance	White to off-white crystalline powder.
CAS	61825-94-3
Formula	C₈H₁₄N₂O₄Pt
MI	14: 6912
MW	397.3
Purity	≥98% (HPLC)
Solubility	Slightly soluble in water (7.9mg/ml); very slightly soluble in methanol; almost insoluble in 100% ethanol.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Omega-3 eicosapentaenoic acid decreases CD133 colon cancer stem-like cell marker expression while increasing sensitivity to chemotherapy: De Carlo, F., Witte, T. R., et al.; PLoS One 8, e69760 (2013), Abstract
Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo: Yamaguchi, T., Kakefuda, R., et al.; Int. J. Oncol. 39, 23 (2011), Abstract
Blocking phosphoinositide 3-kinase activity in colorectal cancer cells reduces proliferation but does not increase apoptosis alone or in combination with cytotoxic drugs: Martin-Fernandez, C., Bales, J., et al.; Mol. Cancer Res. 7, 955 (2009), Abstract

Last modified: May 29, 2024

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Oxaliplatin

ALX-400-042

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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