Omeprazole

Omeprazole inhibits H⁺K⁺-ATPase (IC50 = 5.8 μM). Potent inhibitor of CYP2C19 (Ki=3.1 mM); enhances efficacy of remdesivir (10-fold). Inhibits swelling-dependent chloride channels. Raises stomach pH, which in turn improves oral bioavailability of bioactive peptides such as oxytocin. Displays broad spectrum antiviral activity.