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Omeprazole inhibits H+K+-ATPase (IC50 = 5.8 μM). Potent inhibitor of CYP2C19 (Ki=3.1 mM); enhances efficacy of remdesivir (10-fold). Inhibits swelling-dependent chloride channels. Raises stomach pH, which in turn improves oral bioavailability of bioactive peptides such as oxytocin. Displays broad spectrum antiviral activity.
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RUO – Research Use Only |
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