Omentin (rat), (recombinant)

Omentin (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been identified as a visceral fat (or omental fat) depot-specific adipokine. Omentin is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin triggers AKT signalling in the absence of insulin.