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HDAC inhibitor

Negative control compound for the histone deacetylase (HDAC) inhibitor scriptaid (Prod. No. BML-GR326).

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Alternative Name	4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-N-hydroxybutanamide
Appearance	Yellow to off-white solid.
CAS	300816-11-9
Couple Target	HDAC
Couple Type	Inhibitor
Formula	C₁₆H₁₄N₂O₄
MW	298.3
Purity	≥97% (TLC)
Solubility	Soluble in DMSO (4mg/ml) or ethanol (0.3mg/ml).
Source	Synthetic.

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Epigenetically maintained SW13+ and SW13- subtypes have different oncogenic potential and convert with HDAC1 inhibition: M.R. Davis, et al.; BMC Cancer 16, 316 (2016), Application(s): Cell culture, Abstract — Full Text
A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library: G.H. Su, et al.; Cancer Res. 60, 3137 (2000), Abstract — Full Text

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HDAC inhibitor

Alternative Name	6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide
CAS	287383-59-9
Couple Type	Inhibitor
Purity	≥97% (HPLC)

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