NOR-5

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Nitric oxide donor

Nitric oxide (NO) donor. The half-life time of 0.5mM NOR-5 is 20 hours at 37°C in 0.1M PBS, pH 7.4.

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Alternative Name	(±)-2-((E)-4-Ethyl-3[(Z)-hydroxyimino]6-methyl-5-nitro-heptenyl)-3-pyridinecarboxamide
Appearance	White to off-white powder.
Formula	C₁₆H₂₂N₄O₄
MW	334.4
Purity	≥98% (HPLC)
Solubility	Soluble in DMSO (10mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light and moisture.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection: Nairz, M., Schleicher, U., et al.; J. Exp. Med. 210, 855 (2013), Abstract
Comparison of antiplatelet effects of two nitric oxide-donating agents, FR146801 and FK409: Y. Hirasawa, et al.; Thromb. Haemost. 79, 620 (1998), Abstract
Comparison of hemodynamic effects of nitric oxide (NO) donors with different NO-releasing properties in rats: Y. Kita, et al.; J. Cardiovasc. Pharmacol. 30, 223 (1997), Abstract
Oral biological activities of spontaneous nitric oxide releasers are accounted for by their nitric oxide-releasing rates and oral absorption manners: Y. Kita, et al.; J. Pharmacol. Exp. Ther. 276, 421 (1996), Abstract

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