Nitric oxide donor
Nitric oxide (NO) donor. The half-life time of 0.1mM NOC-12 is 100 min. at 37°C in 0.1M PBS, pH 7.4.
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Product Details
| Alternative Name |
1-Hydroxy-2-oxo-3-(N-ethyl-2-aminoethyl)-3-ethyl-1-triazene |
|---|---|
| Appearance |
White powder. |
| CAS |
146724-89-2 |
| Formula |
C6H16N4O2 |
| MW |
176.2 |
| Purity |
≥97% (HPLC) |
| Solubility |
Soluble in 0.1M NaOH (10mg/ml) |
Handling & Storage
| Use/Stability |
As indicated on product label or CoA when stored as recommended. Prepare fresh stock solution prior to use. Store in ice bath during the experiment. Stock solution will lose 5% of activity per day when stored at -20°C. |
|---|---|
| Handling |
Protect from light and moisture. Packaged under inert gas. |
| Long Term Storage |
-20°C |
| Shipping |
Blue Ice |
| Regulatory Status |
RUO – Research Use Only |
|---|
- Excellent absorption enhancing characteristics of NO donors for improving the intestinal absorption of poorly absorbable compound compared with conventional absorption enhancers: G. Fetih, et al.; Drug Metab. Pharmacokinet. 21, 222 (2006), Abstract — Full Text
- Characterization of the influence of nitric oxide donors on intestinal absorption of macromolecules: K. Takahashi, et al.; Int. J. Pharm. 286, 89 (2004), Abstract
- New nitric oxide-releasing zwitterions derived from polyamines: J.A. Hrabie, et al.; J. Org. Chem. 58, 1472 (1993)
Related Products
| Alternative Name | SIN-1, Linsidomine |
|---|---|
| CAS | 33876-97-0 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |
| Alternative Name | DEA/NO, 2-(N,N-Diethylamino)-diazenolate-2-oxide . diethylammonium salt |
|---|---|
| CAS | 372965-00-9 |
| Purity | ≥97% (NMR) |
| Alternative Name | NOC-18, DETA/NO, (Z)-1-[2-(2-Aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate, 3,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene, 2,2′-(Hydroxynitrosohydrazino)bis-ethanamine |
|---|---|
| CAS | 146724-94-9 |
| Purity | ≥97% (1H-NMR) |
| Alternative Name | Dipropylenetriamine NONOate |
|---|---|
| CAS | 146724-95-0 |
| Purity | ≥98% (NMR) |
Last modified: May 29, 2024
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