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n-Octyl-β-D-thioglucopyranoside

ALX-500-009

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Non-ionic detergent

OTG is a nonionic detergent that may be used to isolate membrane proteins from E. coli without inactivation. Stable in aqueous solution and easily removed by dialysis.

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Product Details

Alternative Name	n-Octyl-β-D-thioglucoside, OTG
Appearance	White to off-white crystalline powder.
CAS	85618-21-9
Formula	C₁₄H₂₈O₅S
Identity	Determined by IR.
MW	308.4
Purity	≥98% (HPLC)
Solubility	Soluble in water (8g/100ml) or methanol.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light. Hygroscopic.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Characterization of mixed non-ionic surfactants n-octyl-beta-D-thioglucoside and octaethylene-glycol monododecyl ether: micellization and microstructure: C.C. Ruiz & J.A. Molina-Bolivar; J. Colloid. Interface Sci. 361, 178 (2011), Abstract
Solubilization and structural stability of bacteriorhodopsin with a mild nonionic detergent, n-Octyl-beta-thioglucoside: A. Asada, & M. Sonoyama; Biosci. Biotechnol. Biochem. 75, 376 (2011), Abstract — Full Text
Development and crystallization of a minimal thermostabilised G protein-coupled receptor: T. Warne, et al.; Protein Expr. Purif. 65, 204 (2009), Abstract
The ABC transporter BmrA from Bacillus subtilis is a functional dimer when in a detergent-solubilized state: S. Ravaud, et al.; Biochem. J. 395, 345 (2006), Abstract — Full Text
Use of n-Octyl-β-D-thioglucopyranoside in the isolation of a bacterial membrane protein: an improved method for immunological applications.: J.M. Peula-Garcia, et al.; J. Surface Sci. Technol. 22, 141 (2006), Full Text
Use of octyl beta-thioglucopyranoside in two-dimensional crystallization of membrane proteins: M. Chami, et al.; J. Struct. Biol. 133, 64 (2001), Abstract
Characteristics of n-octyl beta-D-thioglucopyranoside, a new non-ionic detergent useful for membrane biochemistry: S. Saito & T. Tsuchiya; Biochem. J. 222, 829 (1984), Abstract
Use of n-octyl-beta-D-thioglucoside, a new nonionic detergent, for solubilization and reconstitution of membrane proteins: T. Tsuchiya & S. Saito; J. Biochem. 96, 1593 (1984), Abstract

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n-Octyl-β-D-thioglucopyranoside

ALX-500-009

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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