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This antibody is covered by our Worry-Free Guarantee.
Product Details
| Application |
IHC (FS), WB |
|---|---|
| Clone |
F109.3E1 |
| Formulation |
Sterile filtered supernatant containing 0.1% sodium azide. |
| Host |
Mouse |
| Immunogen |
Both human ventricular myosin light chains. |
| Isotype |
IgG1 |
| Recommendation Dilutions/Conditions |
Immunohistochemistry (frozen sections, can be used undiluted)Western Blot (dilution 1:10)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. |
| Species Reactivity |
Human, Rat |
| Specificity |
Recognizes myosin light chain 2 (LC2) (aa 45-59). |
| Worry-free Guarantee |
This antibody is covered by our Worry-Free Guarantee. |
Handling & Storage
| Long Term Storage |
+4°C |
|---|---|
| Shipping |
Blue Ice |
| Regulatory Status |
RUO – Research Use Only |
|---|
- AGEs induce endothelial cells senescence and endothelial barrier dysfunction via miR-1-3p/MLCK signaling pathways: M. Cheng, et al.; Gene 851, 147030 (2023), Abstract
- Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation: Harlaar, N., Dekker, S. O., et al.; Nat. Biomed. Eng. 6, 389 (2022), Abstract
- Defective coronary vessel organization and reduction of VEGF-A in mouse embryonic hearts with gestational mild hypoxia: Cai, L. X., Alkassis, F. F., et al.; Dev. Dyn. 249, 636 (2020), Abstract
- Diaphragm weakness and proteomics (global and redox) modifications in heart failure with reduced ejection fraction in rats.: Vohra, R., Walter, G. A., et al.; J. Mol. Cell. Cardiol. 139, 238 (2020), Application(s): WB / Reactant(s): Rat, Abstract
- Cardiac MLC2 kinase is localized to the Z-disc and interacts with α-actinin2.: X Cai, L., Tanada, Y., et al.; Sci. Rep. 9, 12580 (2019), Application(s): IHC, IP, WB / Reactant(s): Human, Mouse, Abstract
- Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress.: van Opbergen, C. J. M., Noorman, M., et al.; Int. J. Mol. Sci. 20, (2019), Application(s): IF, IHC-IF, Abstract
- Heterozygous Mylk3 Knockout Mice Partially Recapitulate Human DCM With Heterozygous MYLK3 Mutations.: Tougas, C. L., Grindrod, T., et al.; Front. Physiol. 10, 696 (2019), Application(s): WB, Abstract
- Acute heart failure with cardiomyocyte atrophy induced in adult mice by ablation of cardiac myosin light chain kinase: Massengill, M. T., Ashraf, H. M., et al.; Cardiovasc. Res. 111, 34 (2016), Abstract
- Heart Failure Induced by Perinatal Ablation of Cardiac Myosin Light Chain Kinase.: Kasahara, H., Anderson, R. H., et al.; Front. Physiol. 7, 480 (2016), Application(s): IHC, WB, Abstract
- Myosin regulatory light chain (RLC) phosphorylation change as a modulator of cardiac muscle contraction in disease: Toepfer, C., Caorsi, V., et al.; J. Biol. Chem. 288, 13446 (2013), Abstract
- Attenuated fatigue in slow twitch skeletal muscle during isotonic exercise in rats with chronic heart failure: M. Munkvik, et al.; PLoS One 6, e22695 (2011), Application(s): WB / Reactant(s) Rat, Abstract — Full Text
- Isolation and functional characterization of alpha-smooth muscle actin expressing cardiomyocytes from embryonic stem cells: S.P. Potta; Cell Physiol. Biochem. 25, 595 (2010), Abstract — Full Text
- Causes of fatigue in slow-twitch rat skeletal muscle during dynamic activity: Munkvik, M., Lunde, P. K., et al.; Am. J. Physiol. Regul. Integr. Comp. Physiol. 297, R900 (2009), Abstract
- Differential contribution of cardiac sarcomeric proteins in the myofibrillar force response to stretch: Y. Ait Mou, et al.; Pflugers Arch. 457, 25 (2008), Abstract
- Myofilament degradation and dysfunction of human cardiomyocytes in Fabry disease: C. Chimenti, et al.; Am. J. Pathol. 172, 1482 (2008), Abstract
- Length and protein kinase A modulations of myocytes in cardiac myosin binding protein C-deficient mice: O. Cazorla, et al.; Cardiovasc. Res. 69, 370 (2006), Abstract — Full Text
- Cardiomyocyte stiffness in diastolic heart failure: A. Borbely, et al.; Circulation 111, 774 (2005), Abstract — Full Text
- Transmural stretch-dependent regulation of contractile properties in rat heart and its alteration after myocardial infarction: O. Cazorla, et al.; FASEB J. 19, 88 (2005), Abstract — Full Text
- Probing conformational changes within LC2 domains of cardiac myosin: P. Eldin, et al.; Biochemistry 33, 12558 (1994), Abstract
- Probing myosin light chain 1 structure with monoclonal antibodies: B. Cornillon, et al.; J. Mus. Res. Cell. Motility 13, 329 (1992), Abstract
Last modified: May 29, 2024
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