Home Shop MVP/LRP (human) monoclonal antibody (LRP-56)

MVP/LRP (human) monoclonal antibody (LRP-56)

ALX-801-005

11 citations

Datasheet
Manual
SDS
CofA

Already have an account?

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

This antibody is covered by our Worry-Free Guarantee.

MVP/LRP (human) monoclonal antibody (LRP-56) image — **Figure:** Liver cells stained with LRP-56 (ALX-801-005).

Product Details

Alternative Name	Major vault protein/Lung resistance protein
Application	Flow Cytometry, ICC, IHC (FS), IHC (PS)
Application Notes	Flow Cytometry: cell permeabilization required) Immunocytochemistry: cytospin preparations
Clone	LRP-56
Formulation	Liquid. In serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide.
Host	Mouse
Immunogen	Human MVP/LRP (major vault protein/lung resistance protein).
Isotype	IgG2b
Positive Control	Cell lines: Appropriate drug-sensitive parental cell lines and their multdrug resistant derivatives prepared by the same methods as the test specimens should be used as control materials. Tissue: Human colon, kidney, bronchus or adrenal are recommended.
Recommendation Dilutions/Conditions	Recommended starting dilution is 1:20. Suggested dilutions/conditions may not be available for all applications. Optimal should be determined individually for each application.
Species Reactivity	Human
Specificity	Recognizes an internal epitope (P110) of human MVP/LRP, which is overexpressed in various human non-P-glycoprotein MDR tumor cell lines.
UniProt ID	Q14764
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Short Term Storage	+4°C
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

MVP Expression Facilitates Tumor Cell Proliferation and Migration Supporting the Metastasis of Colorectal Cancer Cells.: Ivanov, P., Rucinski, M., et al.; Int. J. Mol. Sci. 22, (2021), Application(s): ICC / Reactant(s): Human, Abstract
Biological activity of PtIV prodrugs triggered by riboflavin-mediated bioorthogonal photocatalysis.: Alonso-de Castro, S., Terenzi, A., et al.; Sci. Rep. 8, 17198 (2018), Application(s): WB, Abstract
The major vault protein is responsive to and interferes with interferon-gamma-mediated STAT1 signals: Steiner, E., Holzmann, K., et al.; J. Cell Sci. 119, 459 (2006), Abstract
The formation of vault-tubes: a dynamic interaction between vaults and vault PARP: A. Van Zon, et al.; J. Cell Sci. 116, 4391 (2003), Abstract
Detection of the Mr 110,000 lung resistance-related protein LRP/MVP with monoclonal antibodies: A.B. Schroeijers, et al.; J. Histochem. Cytochem. 49, 1379 (2001), Abstract
Immunohistochemical analysis of drug resistance-associated proteins in ovarian carcinomas: D. Mayr, et al.; Pathol. Res. Pract. 196, 469 (2000), Abstract
The Mr 193,000 vault protein is up-regulated in multidrug-resistant cancer cell lines: A.B. Schroeijers, et al.; Cancer Res. 60, 1104 (2000), Abstract — Full Text
Immunohistochemical detection of the human major vault protein LRP with two monoclonal antibodies in formalin-fixed, paraffin-embedded tissues: A.B. Schroeijers, et al.; Am. J. Pathol. 152, 373 (1998), Abstract
Identification of novel drug resistance-associated proteins by a panel of rat monoclonal antibodies: M.J. Flens, et al.; Int. J. Cancer 73, 249 (1997), Abstract
Membrane transport proteins associated with drug resistance expressed in human melanoma: D. Schadendorf, et al.; Am. J. Pathol. 147, 1545 (1995), Abstract

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Datasheet

Certificate of Analysis

Please enter the lot number as featured on the product label

Lot No. :

SDS

Enzo Life Science provides GHS Compliant SDS

English (EU) SDS

If your language is not available please fill out the SDS request form

Your Cart

Your Cart

MVP/LRP (human) monoclonal antibody (LRP-56)

ALX-801-005

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Change Country

Tell us about You

Tell us about your paper

Tell us about You

Tell us about your project