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GABA_A receptor agonist

Potent GABA_A receptor agonist.

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Alternative Name	3-Hydroxy-5-aminomethylisoxazole
Appearance	White to off-white solid.
CAS	2763-96-4
Couple Target	GABA receptor
Couple Type	Activator, Ligand
Formula	C₄H₆N₂O₂
MI	14: 6312
MW	114.1
Purity	≥98% (TLC)
RTECS	NY3325000
Solubility	Very soluble in water (10mg/ml) or methanol; soluble in 100% ethanol.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Control of Feeding Behavior by Cerebral Ventricular Volume Transmission of Melanin-Concentrating Hormone: Noble, E. E., Hahn, J. D., et al.; Cell Metab. 28, 55 (2018), Abstract
The human neuroblastoma cell line, IMR-32 possesses a GABAA receptor lacking the benzodiazepine modulatory site: S.M. Anderson, et al.; Neuropharmacology 32, 455 (1993), Abstract
Physiological and behavioral studies with muscimol: F.V. DeFeudis; Neurochem. Res. 5, 1047 (1980), Abstract

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