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Mouse Interferon Beta

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E.coli expressed Mouse IFN Beta protein with a single non-glycosylated polypeptide chain
Increased stability with engineered disulfide bond
95% or greater purity

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Alternative Name	Interferon-β, IFN-β
Endotoxin Content	< 1 EU/μg
Formulation	Liquid. In PBS containing 0.1% BSA.
MW	~19.7kDa
Purity	≥95%
Purity Detail	A combination of ion exchange, hydrophobic interaction and size exclusion chromatography.
Quantity	0.1ml
Source	Produced in E. coli.

Use/Stability	Thaw product vial by incubation in cold tap water until just thawed. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Handling	Avoid freeze/thaw cycles.
Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Inhibition of Aurora kinase induces endogenous retroelements to induce a type I/III interferon response via RIG-I: L. Choy, et al.; Cancer Res. Commun. 4, 540 (2024), Abstract
PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection: M. Baran, et al.; Cell Rep. 42, 112341 (2023), Abstract
LincRNA-EPS impairs host antiviral immunity by antagonizing viral RNA-PKR interaction: J. Zhu, et al.; EMBO Rep. 23, 53937 (2022), Abstract
Immunostimulatory bacterical antigen-armed oncolytic measles virotherapy significantly increases the potency of anti-PD1 checkpoint therapy: E. Panagioti, et al.; J. Clin. Invest. 131, e141614 (2021), Abstract

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