Home Shop Molsidomine

Molsidomine

ALX-430-003

Datasheet
Manual
SDS
CofA

Already have an account?

NO releasing vasodilator

Long acting antianginal drug that is enzymatically converted in the liver to yield the active metabolite SIN-1 (Prod. No. BML-CN245). NO releasing vasodilator.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Product Details

Alternative Name	N-(Ethoxycarbonyl)-3-(4-morpholinyl)sydnoneimine, Morsidomine, SIN-10
Appearance	White solid.
CAS	25717-80-0
Formula	C₉H₁₄N₄O₄
Identity	Determined by NMR.
MI	14: 6234
MW	242.2
Purity	≥98% (TLC)
Solubility	Soluble in methanol.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Nitric oxide donor molsidomine attenuates psychotomimetic effects of the NMDA receptor antagonist MK-801: N. Pitsikas, et al.; J. Neurosci. Res. 84, 299 (2006), Abstract
Molsidomine, a nitric oxide donor and L-arginine protects against rhabdomyolysis-induced myoglobinuric acute renal failure: V. Chander & K. Chopra; Biochim. Biophys. Acta 1723, 208 (2005), Abstract
Long-term treatment with the NO-donor molsidomine reduces circulating ICAM-1 levels in patients with stable angina: C. Van Hove, et al.; Atherosclerosis 180, 399 (2005), Abstract
Intrarenal administration of molsidomine, a molecule releasing nitric oxide, reduces renal ischemia-reperfusion injury in rats: A. Rodriguez-Pena, et al.; Am. J. Transplant. 4, 1605 (2004), Abstract
Molsidomine: alternative approaches to treat myocardial ischemia: R.-E. Nitz & V.B. Fiedler; Pharmacotherapy 7, 28 (1987), Abstract
Heilmittelchemische Studien In Der Heterocyclischen Reihe 35. Mitteilung. Über Sydnonimine. I. Herstellung und Eigenschaften von Sydnonimin-Salzen: H.U. Daeniker & J. Druey; Helv. Chim. Acta 45, 2426 (1962)