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MMP-3 inhibitor

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Inhibitor of matrix metalloproteinase 3 (MMP-3) (IC₅₀=5µM).

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Alternative Name	Ac-RCGVPD-NH2, Stromelysin-1 inhibitor, Matrix metalloproteinase 3 inhibitor
Appearance	White to off-white solid.
CAS	158841-76-0
Formula	C₂₇H₄₆N₁₀O₉S
MW	686.8
Purity	≥95% (HPLC)
Sequence	Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂
Solubility	Soluble in water.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Potent peptide inhibitors of stromelysin based on the prodomain region of matrix metalloproteinases: N. Fotouhi, et al.; J. Biol. Chem. 269, 30227 (1994), Abstract
Peptides based on the conserved predomain sequence of matrix metalloproteinases inhibit human stromelysin and collagenase: A.C. Hanglow, et al.; Agents Actions 39, C148 (1993), Abstract

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