Home Shop MK-2206 . 2HCl

MK-2206 . 2HCl

Already have an account?

Highly selective inhibitor of Akt1, Akt2 and Akt3

MK-2206 is a highly selective inhibitor of Akt1, Akt2 and Akt3 with IC₅₀ of 8 nM, 12 nM and 65 nM, respectively.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Appearance	Yellow powder.
CAS	1032350-13-2
Couple Target	Akt
Couple Type	Inhibitor
Formula	C₂₅H₂₁N₅O . 2HCl
Identity	Determined by NMR
MW	480.4
Purity	≥99% (HPLC)
Solubility	Soluble in DMSO (14mg/ml) or ethanol (1mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended.
Short Term Storage	+4°C
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence: Kahlhofer, J., Marchet, N., et al.; bioRxiv , (2024)
Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer’s disease models: M. Fassler, et al.; J. Neuroinflammation 18, 19 (2021), Abstract — Full Text
EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis: Lee, S. W., Zhang, Y., et al.; Dev. Cell 50, 381 (2019), Abstract
Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma: Haas, T. L., Sciuto, M. R., et al.; Cell Stem Cell 21, 35 (2017), Abstract

Datasheet, Manuals, SDS & CofA

Please enter the lot number as featured on the product label

Lot No. :

Enzo Life Science provides GHS Compliant SDS

If your language is not available please fill out the SDS request form