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Mevastatin sodium

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HMG-CoA reductase inhibitor

This is the active carboxylate form of mevastatin. It is active in whole cells as well as in cell free assays.

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Appearance	White to off-white solid.
CAS	99782-89-5
Couple Target	HMG-CoA reductase
Couple Type	Inhibitor
Formula	C₂₃H₃₅O₆. Na
MW	430.5
MeltingPoint	44-45°C
Purity	≥98% (HPLC)
Solubility	Soluble in ethanol (20 mg/ml) and DMSO (30 mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

The discovery and development of HMG-CoA reductase inhibitors: A. Endo, et al.; J. Lipid Res. 33, 1569 (1992), Abstract — Full Text
Essential role for mevalonate synthesis in DNA replication: V. Quesney-Huneeus, et al.; Proc. Natl. Acad. Sci. USA 76, 5056 (1979), Abstract — Full Text

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