Home Shop Melanoma marker (human) monoclonal antibody (HMB45) (Ready-to-Use)

Melanoma marker (human) monoclonal antibody (HMB45) (Ready-to-Use)

ENZ-30930

8 citations

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This antibody is covered by our Worry-Free Guarantee.

Melanoma marker (human) monoclonal antibody (HMB45) (Ready-to-Use) Immunohistochemistry — Figure 1. Immunohistochemistry analysis of human melanoma skin tissue using Melanoma marker (human) mAb (HMB45) (Ready-To-Use), (Prod. No. ENZ-30930). Antibody is applied as is.

Product Details

Application	IHC (PS)
Clone	HMB45
Crossreactivity	Does not cross-react with normal melanocytes, intradermal nevus cells or other neoplasms including sarcomas, carcinomas and glial tumors.
Formulation	Liquid. Ready-to-use solution in PBS containing 0.1% sodium azide and 1% BSA.
Host	Mouse
Immunogen	Human axillary lymph node tissue containing pigmented melanoma metastases.
Isotype	IgG1
Purity Detail	Affinity purified.
Recommendation Dilutions/Conditions	Immunohistochemistry (paraffin sections; this antibody can be used for staining of paraffin-embedded tissue sections fixed in neutral buffered formalin and is compatible with most commonly used histological fixatives. Choose a good quality enzyme-linked anti-mouse IgG1 antibody for detection). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually.
Source	Purified from ascites.
Species Reactivity	Human
Specificity	Recognizes a human melanoma-specific antigen present in melanocytic cells and junctional nevi.
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Handling	Avoid freeze/thaw cycles.
Long Term Storage	+4°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Intra- and Inter-Tumor BRAF Heterogeneity in Acral Melanoma: An Immunohistochemical Analysis.: Ito, T., Kaku-Ito, Y., et al.; Int. J. Mol. Sci. 20, (2019), Application(s): IHC / Reactant(s): Human, Abstract
Identification of an Immunogenic Subset of Metastatic Uveal Melanoma: Rothermel, L. D., Sabesan, A. C., et al.; Clin. Cancer Res. 22, 2237 (2016), Abstract
Sclerosing Epithelioid Fibrosarcoma of the Kidney: Clinicopathologic and Molecular Study of a Rare Neoplasm at a Novel Location: C.H. Ohlmann, et al.; Ann. Diagn. Pathol. 19, 221 (2015), Application(s): Immunohistochemistry, Abstract
Melanoma cell heterogeneity. A study of two monoclonal antibodies compared with S-100 protein in paraffin sections: P.H. Duray, et al.; Cancer 61, 2460 (1988), Abstract
Comparison of HMB-45 monoclonal antibody and S-100 protein in the immunohistochemical diagnosis of melanoma: N.G. Ordonez, et al.; Am. J. Clin. Pathol. 90, 385 (1988), Abstract
Immunohistochemical diagnosis of sinonasal melanoma, carcinoma, and neuroblastoma with monoclonal antibodies HMB-45 and anti-synaptophysin: M.R. Wick, et al.; Arch. Pathol. Lab. Med. 112, 616 (1988), Abstract
Recognition of malignant melanoma by monoclonal antibody HMB-45. An immunohistochemical study of 200 paraffin-embedded cutaneous tumors: M.R. Wick, et al.; J. Cutan. Pathol. 15, 201 (1988), Abstract
Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes: A.M. Gown, et al.; Am. J. Pathol. 123, 195 (1986), Abstract — Full Text

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Melanoma marker (human) monoclonal antibody (HMB45)

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Application	IHC (PS)
Host	Mouse
Isotype	IgG1
Species Reactivity	Human

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Melanoma marker (human) monoclonal antibody (HMB45) (Ready-to-Use)

ENZ-30930

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

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