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Me-7BIO

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Control compound for 6BIO (Prod. No. ALX-430-156).

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Alternative Name	(2’Z,3’E)-7-Bromo-1-methylindirubin-3’-oxime
Appearance	Dark red to dark brown solid.
Formula	C₁₇H₁₂BrN₃O₂
MW	370.2
Purity	≥98%
Solubility	Soluble in DMSO.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

An integrated computational approach to the phenomenon of potent and selective inhibition of aurora kinases B and C by a series of 7-substituted indirubins: V. Myrianthopoulos, et al.; J. Med. Chem. 50, 4027 (2007), Abstract
7-Bromoindirubin-3’-oxime induces caspase-independent cell death: J. Ribas, et al.; Oncogene 25, 6304 (2006), Abstract
3’-Substituted 7-halogenoindirubins, a new class of cell death inducing agents: Y. Ferandin, et al.; J. Med. Chem. 49, 4638 (2006), Abstract