LVV Hemorphin 7 ELISA kit

• Sensitive – reliably measure as little as 6.1pg/ml of LVV Hemorphin 7
• Rapid – results in just 3 hours from up to 40 samples in duplicate
• Specific – low cross-reactivity to similar peptides
• Easy-to-use – liquid color-coded reagents reduce errors

The LVV Hemorphin 7 EIA kit is a colorimetric, competitive immunoassay kit with results in just 3 hours.

Hemorphins are opioid peptides derived by proteolysis from hemoglobin. Their sequences are identical in several mammalian species including human, sheep and bovine. LVV hemorphin 7 (LVVYPWTQRF) binds strongly to the Angiotensin IV (AT4) receptors in the brain. The AT4 receptor is an integral membrane aminopeptidase also known as IRAP (insulin regulated membrane aminopeptidase). LVV hemorphin 7 and AT4 are not substrates but rather inhibitors of the AT4 (IRAP) receptor. Both promote learning and memory and reverse amnesia in animal models. Elevated serum levels of LVV Hemorphin 7 have also been documented in patients with some forms of breast cancers that are associated with an increased expression of cathespins B and D.