LTB₄ ELISA kit

• Ultrasensitive measurement of LTB₄, detecting as little as 5.63 pg/ml
• Widely cited in numerous peer-reviewed publications
• Broad dynamic range suitable for a large variety of samples
• High throughput format with results in 4 hours for up to 39 samples in duplicate
• Highly reproducible results day-after-day and lot-after-lot
• Fully quantitative results that surpass semi-quantitaive Western blot analysis

The LTB₄ EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 4 hours. Absorbance is read at 405 nm. Assay up to 39 samples in duplicate with a broad dynamic range that is suitable for a wide variety of sample matrices. Document your results to scientists world-wide with this highly cited kit.

Leukotrienes are major products of 5-lipoxygenase metabolism of arachidonic acid. Leukotriene B₄ (LTB₄) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB₄ has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC₄, LTD₄, and LTE₄) are formed by addition of cysteine derivatives to LTA₄. The conversion of LTA₄ to LTC₄ by the enzyme LTC₄ synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.