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LS E3 1017 is a derivative of thalidomide (Cat.No. PC-1006) and is commonly used as a precursor to PROTACs that hijack cereblon as the E3 ubiquitin ligase component. It is supplied with a carboxylic acid functional handle at a position known not to significantly affect binding to cereblon, for ready conjugation to a linker/target protein ligand.
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| Regulatory Status |
RUO – Research Use Only |
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