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LRRC32 monoclonal antibody (Plato-1) (PE conjugate)

ALX-804-867PE

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LRRC32 (leucine rich repeat containing 32; also known as GARP or Garpin; Glycoprotein A repetitions predominant) is a glycoprotein expressed on the cell surface of megakaryocytes, platelets and activated regulatory T (Treg) cells.

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This antibody is covered by our Worry-Free Guarantee.

LRRC32 monoclonal antibody (Plato-1) (PE conjugate) Flow Cytometry — Flow cytometry analysis, intracellular stained, of 10⁶ Jurkat cells using LRRC32, mAb (Plato-1) (PE conjugate) at a concentration of 10μg/ml.

Product Details

Alternative Name	Leucine-rich repeat-containing protein 32, GARP, Garpin, Glycoprotein A repetitions predominant
Application	Flow Cytometry
Application Notes	Detects a band of ~100kDa by Western blot. Native protein is ~72kDa.
Clone	Plato-1
Formulation	Liquid. In PBS containing 0.09% sodium azide.
Host	Mouse
Immunogen	Recombinant human LRRC32 (aa 20-627).
Isotype	IgG2b
Purity Detail	Protein G-affinity purified.
Recommendation Dilutions/Conditions	Flow Cytometry (1:100)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Source	Purified from concentrated hybridoma tissue culture supernatant.
Species Reactivity	Human, Mouse
UniProt ID	Q14392
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Use/Stability	Stable for at least 1 year after receipt when stored at -20°C.
Handling	Keep conjugated formats at +4°C. Do not freeze. Protect from light.
Short Term Storage	+4°C
Long Term Storage	+4°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Therapeutic potential of FOXP3+ regulatory T cells and their interactions with dendritic cells: D.Q. Tran & E.M. Shevach; Hum. Immunol. 70, 294 (2009), Abstract
Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells: R. Wang, et al.; PNAS 106, 13439 (2009), Abstract
GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells: D.Q. Tran, et al.; PNAS 106, 13445 (2009), Abstract

Related Products

LRRC32 (human):Fc (human), (recombinant)

ALX-522-117

Alternative Name	Leucine-rich repeat-containing protein 32, GARP, Garpin, Glycoprotein A repetitions predominant
Purity	≥90% (SDS-PAGE)
Source	Produced in CHO cells. Human LRRC32 (aa 20-627) is fused to the Fc portion of human IgG1.

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LRRC32 monoclonal antibody (Plato-1) (PE conjugate)

ALX-804-867PE

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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