Home Shop Leukotriene A4 methyl ester

Leukotriene A4 methyl ester

BML-LA004

Datasheet
Manual
SDS
CofA

Already have an account?

Substrate for LTA₄ hydrolase and LTC₄ synthase

Unstable intermediate in the biosynthesis of LTB₄ and LTC₄. The naturally occuring free acid is a substrate for LTA₄ hydrolase and LTC₄ synthase and plays a central role in transcellular leukotrieneand lipoxin biosynthesis. Mobilizes Ca²⁺ in human neutrophils. Supplied as the methyl ester for greater stability.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Product Details

Alternative Name	LTA4-ME
Appearance	Liquid.
CAS	73466-12-3
Couple Target	Leukotriene hydrolase, Leukotriene synthase, Prostanoid receptor
Couple Type	Ligand, Substrate
Formula	C₂₁H₃₂O₃
Formulation	Oil dissolved in 2% triethylamine/hexane.
MW	332.5
Purity	≥95% (HPLC) (remainder 11-trans isomer)
Source	Synthetic.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored, as supplied, at -80°C.
Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils: S. Fiore & C. N. Serhan; J. Exp. Med. 172, 1451 (1990), Abstract — Full Text
Ca2+ mobilization with leukotriene A4 and epoxytetraenes in human neutrophils: F. Luscinskas, et al.; Biochem. Pharmacol. 39, 355 (1990), Abstract
Enzymes involved in the biosynthesis of leukotriene B4: B. Samuelsson & C. D. Funk; J. Biol. Chem. 264, 19469 (1989), Abstract — Full Text
Leukotrienes and lipoxins: structures, biosynthesis, and biological effects: B. Samuelsson, et al.; Science 237, 1171 (1987), Abstract

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Datasheet

Certificate of Analysis

Please enter the lot number as featured on the product label

Lot No. :

SDS

Enzo Life Science provides GHS Compliant SDS

English (EU) SDS

If your language is not available please fill out the SDS request form

Your Cart

Your Cart

Leukotriene A4 methyl ester

BML-LA004

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Change Country

Tell us about You

Tell us about your paper

Tell us about You

Tell us about your project