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Potent and selective FLT3 inhibitor. Inhibits RET and RET phosphorylation in medullary thyroid carcinoma cells. Suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders. Potent Trk inhibitor. Cell permeable.
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RUO – Research Use Only |
|---|
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| CAS | 38966-21-1 |
|---|---|
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| Alternative Name | 6-(6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6,8-dihydrofuro[3,4-E][1,3]benzodioxol-8-ol, (+)-Decumbensine |
|---|---|
| CAS | 6883-44-9 |
| Purity | ≥98% (HPLC) |
| Alternative Name | (3S,3aR,4R,4aS,8aR,9aS)-4-[(1E)-2-[(2R,6S)-1,6-Dimethyl-2-piperdinyl]ethenyl]decahydro-3-methyl-naphtho[2,3-c]furan-1(3H)-one |
|---|---|
| CAS | 6879-74-9 |
| Couple Type | Inhibitor |
| Purity | ≥98% |
