Leptin, Pegylated (human), (recombinant)

Recombinant mouse pegylated leptin is capable of stimulatng proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its in vitro activity is 5-7 fold lower than the non-pegylated recombinant human leptin but in vivo it has profound weight reducing effect (as compared to the non-pegylated recombinant human leptin), resulting mainly from reduced food intake.

< 0.1 ng/µg of protein (<1EU/µg)

Lyophilized.

35.6 kDa

> 98.0% as determined by Gel filtration and SDS-PAGE gel.

Produced in E. coli.

P41159