L-NASPA

BML-LP101

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LPA receptor ligand

L-NASPA is an antagonist of LPA-induced platelet aggregation and chloride conductance in Xenopus oocytes. In human breast carcinoma MDA-MB231 cells it is a potent LPA agonist.

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Product Details

Alternative Name	N-Palmitoyl-L-serine phosphoric acid
Appearance	White to off-white solid.
CAS	155915-46-1
Couple Target	LPA receptor
Couple Type	Ligand
Formula	C₁₉H₃₈NO₇P . H₂O
MW	440.5
Purity	≥98% (TLC)
Solubility	Soluble in DMSO (10 mg/ml)or ethanol (10 mg/ml).

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at -80°C for up to 1 year. Store solutions at -20°C for up to 1 year.
Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Characterization of a receptor subtype-selective lysophosphatidic acid mimetic: S. B. Hooks, et al.; Mol. Pharmacol. 53, 188 (1998), Abstract — Full Text
N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors: K. Liliom, et al.; Mol. Pharmacol. 50, 616 (1996), Abstract
Biochemical characterization of the interaction of lipid phosphoric acids with human platelets: comparison with platelet activating factor: T. Sugiura, et al.; Arch. Biochem. Biophys. 311, 358 (1994), Abstract

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L-NASPA

BML-LP101

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

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