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L-NAME . hydrochloride

ALX-105-003

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NOS inhibitor

Inhibitor of nitric oxide synthase (NOS). More soluble than N^G-Nitro-L-arginine (Prod. No. ALX-105-001). Suppresses the release of nitric oxide (NO) from endothelial cells. Has a different effect on the superoxide generation by NOS than L-NMMA (Prod. No. ALX-106-001).

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Product Details

Alternative Name	NG-Nitro-L-arginine-methyl ester . HCl
Appearance	White to off-white solid.
CAS	51298-62-5
Couple Target	NOS
Couple Type	Inhibitor
Formula	C₇H₁₅N₅O₄ . HCl
MW	233.2 . 36.5
Purity	≥98% (TLC)
Solubility	Soluble in water (50mg/ml) or methanol (25g/ml).

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Human airway tuft cells influence the mucociliary clearance through cholinergic signalling: M.I. Hollenhorst, et al.; Respir. Res. 24, 267 (2023), Abstract
Anti-inflammatory Role of Carotenoids in Endothelial Cells Derived from Umbilical Cord of Women Affected by Gestational Diabetes Mellitus: M. Cucci, et al.; Oxid. Med. Cell. Longev. 2019, 8184656 (2019), Abstract — Full Text
Nitric oxide radicals are emitted by wasp eggs to kill mold fung: E. Strohm, et al.; Elife 8, e43718 (2019), Abstract — Full Text
Endothelium- and smooth muscle-dependent vasodilator effects of Citrus aurantium L. var. amara: Focus on Ca2+ modulation: P. Kang, et al.; Biomed. Pharmacother. 82, 467 (2016), Application(s): Cell culture, Abstract
Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo: K. Ashina, et al.; PLoS One 10, e0132367 (2015), Application(s): Cell Culture, Abstract — Full Text
Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis: Kindrachuk, J., Ork, B., et al.; Antimicrob. Agents Chemother. 59, 1088 (2015), Abstract
Vasodilation by GPER in mesenteric arteries involves both endothelial nitric oxide and smooth muscle cAMP signaling: Lindsey, S. H., Liu, L., et al.; Steroids 81, 99 (2014), Abstract
Nitric oxide regulates BAFF expression and T cell-independent antibody responses: Giordano, D., Draves, K. E., et al.; J. Immunol. 193, 1110 (2014), Abstract
From blue light to clock genes in zebrafish ZEM-2S cells: Ramos, B. C., Moraes, M. N., et al.; PLoS One 9, e106252 (2014), Application(s): In Vitro, Abstract
Circadian phase-dependent effect of nitric oxide on L-type voltage-gated calcium channels in avian cone photoreceptors: Ko, M. L., Shi, L., et al.; J. Neurochem. 127, 314 (2013), Abstract

Related Products

L-NMMA . monoacetate

ALX-106-001

NOS inhibitor

13 citations

Alternative Name	NG-Monomethyl-L-arginine . monoacetate
CAS	53308-83-1
Couple Type	Inhibitor
Purity	≥99% (TLC)

ALX-106-001-M025 — 25 mg

$77.00

L-NMMA . monoacetate quantity
ALX-106-001-M100 — 100 mg

$278.00

L-NMMA . monoacetate quantity
ALX-106-001-G001 — 1 g

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L-NMMA . monoacetate quantity

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L-NAME . hydrochloride

ALX-105-003

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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SDS

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