Carnitine is a critical transport molecule which shuttles fatty acids into the mitochondria where they are utilized to make acetyl CoA, a key part of the TCA cycle. In the reverse direction carnitine shuttles toxic by-products of fatty acid metabolism out of the mitochondria, minimizing oxidative stress and oxidative damage that would otherwise occur. L-Carnitine is synthesized from methionine and lysine. Beyond its highly important shuttle function, it also enhances insulin sensitivity and cellular glucose uptake. AkrivisBio’s L-Carnitine Assay is a simple, sensitive means of measuring free L-Carnitine in biological samples.
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