KS-176

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BCRP inhibitor

A potent specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2).
IC₅₀=1.39µM

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Alternative Name	N-(4-(2-hydroxyethyl)phenyl)-2-(4-nitrobenzamido)benzamide
Appearance	Pale yellow solid.
Couple Target	BCRP
Couple Type	Inhibitor
Formula	C₂₂H₁₉N₃O₅
MW	405.4
Purity	≥98% (TLC)
Solubility	Soluble in 100% ethanol, methanol or DMSO.

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored at -20°C. Stock solutions are stable for up to 2 months at -20°C.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Specific inhibitors of the breast cancer resistance protein (BCRP): A. Pick, et al.; Chem. Med. Chem. 5, 1498 (2010), Abstract

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