K6 Tetra-Ubiquitin (Ub4) (S20C) Mutant
LSI-SI-0624
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Mitophagy (the autophagic processing of damaged mitochondria) via Parkin activation is mainly promoted by K6 and K63 linked chains. K6-linked ubiquitination is also a main contributor to the DNA damage response and acts as a DNA-binding enhancer during the innate immune system response. These chain types are also involved in protein stabilization and other non-degradative processes. The serine in position 20 has been changed to a cysteine.
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Regulatory Status |
RUO – Research Use Only |
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