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K6 Tetra-Ubiquitin (Ub4) (S20C) Mutant

LSI-SI-0624

  • LSI-SI-0624-0025   —   25 µg
    $374.00
  • LSI-SI-0624-0050   —   50 µg
    $525.00

Mitophagy (the autophagic processing of damaged mitochondria) via Parkin activation is mainly promoted by K6 and K63 linked chains.  K6-linked ubiquitination is also a main contributor to the DNA damage response and acts as a DNA-binding enhancer during the innate immune system response.  These chain types are also involved in protein stabilization and other non-degradative processes. The serine in position 20 has been changed to a cysteine.

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Regulatory Status

RUO – Research Use Only