ITSA-1

BML-GR350

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HDAC inhibitor

ITSA-1 is a cell permeable benzotriazole amide that counteracts trichostatin A (Prod. No. BML-GR309) induced cell cycle arrest, histone acetylation and transcriptional activation but not the activity of other HDAC inhibitors.

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Product Details

Alternative Name	N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide
Appearance	White solid.
CAS	200626-61-5
Couple Target	HDAC
Couple Type	Inhibitor
Formula	C₁₃H₇Cl₂N₃O
MW	292.1
Purity	≥98% (TLC)
Solubility	Soluble in DMSO (25mg/ml).

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored, as supplied, at room temperature. Stock solutions are stable for up to 3 months at -20°C.
Handling	Protect from light. Packaged under inert gas.
Long Term Storage	Ambient
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation: K.M. Koeller, et al.; Chem. Biol. 10, 397 (2003), Abstract
Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays: S.J. Haggarty, et al.; Chem. Biol. 10, 383 (2003), Abstract

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ITSA-1

BML-GR350

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

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