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ITP-γ-S is a phosphorothioate-modified analogue of ITP with increased metabolic stability which can be useful for modification with SH-reactive reporters or for connection to structures with SH-groups via a disulfide bond. The parent compound ITP is an intermediate in the purine metabolism pathway. Gille et al. (2004) reported ITP-γ-S to be a mixed G-protein activator and adenylyl cyclase (AC) inhibitor.
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| Regulatory Status |
RUO -Research Use Only |
|---|
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| CAS | 88453-52-5 |
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| Alternative Name | Guanosine-5′-O-(3-thiotriphosphate) . tetrasodium salt |
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| Couple Type | Modified nucleotides |
| Purity | > 95% HPLC |
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| Couple Type | Modified nucleotides |
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| Couple Type | Modified nucleotides |
| Purity | > 95% HPLC for mixture |