Home Shop Isolectin B4 (Bandeiraea simplicifolia), (FITC conjugate)

Isolectin B₄ (Bandeiraea simplicifolia), (FITC conjugate)

ALX-650-001F

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BS-I is a tetrameric lectin consisting of two types of subunits designated A and B. There are five BS-I isolectins with different subunit composition: BSI-B₄, BSI-AB₃, BSI-A₂B₂, BSI-A₃B and BSI-A₄.
BSI-B₄ is blood group B specific and has an exclusive affinity for terminal α-D-galactosyl residues, whereas BSI-A₄ has blood group A specificity and has a major affinity for terminal N-acetyl-α-D-galactosaminyl residues.

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Product Details

Activity	Agglutinates blood group B glutaraldehyde-fixed human red blood cells at a concentration of ~2µg/ml. No agglutination of blood group A, glutaraldehyde-fixed human red blood cells occurred at concentrations up to ~100µg/ml.
Alternative Name	Isolectin B4 (Griffonia simplicifolia), BSI-B4
Concentration	1mg/ml
Formulation	Liquid. In 10mM HEPES, pH 7.5, containing 0.15M sodium chloride, 0.08% sodium azide and 0.1mM Ca²⁺.
Quality Control	Free Fluorescein F/P (molar) Active Conjugate
Source	Isolated from Griffonia (Bandeiraea) simplicifolia seeds.
Specificity	Binds to α-(1,3) galactosyl galactoside epitopes.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Prepare fresh dilutions prior to each application.
Handling	Protect from light.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Elimination of GGTA1, CMAH, β4GalNT2 and CIITA genes in pigs compromises human versus pig xenogeneic immune reactions: Xu, J., Ren, J., et al.; Animal Model Exp. Med. 7, 584 (2024), Abstract
Large-Scale Formation and Long-Term Culture of Hepatocyte Organoids From Streamlined In Vivo Genome-Edited GGTA1-/- Pigs for Bioartificial Liver Applications: He, Y., Gao, M., et al.; Xenotransplantation 31, e12878 (2024), Abstract
Production of four-gene (GTKO/hCD55/hTBM/hCD39)-edited donor pigs and kidney xenotransplantation: Yang, C., Wei, Y., et al.; bioRxiv , (2024)
Design and testing of a humanized porcine donor for xenotransplantation: Anand, R. P., Layer, J. V., et al.; Nature 622, 393 (2023), Abstract
Caspase-8 Modulates Angiogenesis By Regulating A Cell Death Independent Pathway In Endothelial Cells: Tisch, N., Freire-Valls, A., et al.; bioRxiv , (2019)
Caspase-8 modulates physiological and pathological angiogenesis during retina development: Tisch, N., Freire-Valls, A., et al.; J. Clin. Invest. 129, 5092 (2019), Abstract
CD55 upregulation in astrocytes by statins as potential therapy for AQP4-IgG seropositive neuromyelitis optica: Tradtrantip, L., Duan, T., et al.; J. Neuroinflammation 16, 57 (2019), Abstract
The signaling lipid sphingosine 1-phosphate regulates mechanical pain: R.Z. Hill, et al.; Elife 7, e33285 (2018), Application(s): IHC / Reactant(s): Mouse, Abstract — Full Text
Oxaliplatin-induced changes in expression of transient receptor potential channels in the dorsal root ganglion as a neuropathic mechanism for cold hypersensitivity: A. Xhukyo, et al.; Neuropeptides 67, 95 (2018), Abstract
Neuronal NTPDase3 Mediates Extracellular ATP Degradation in Trigeminal Nociceptive Pathway: L. Ma, et al.; PLoS One 11, e0164028 (2016), Abstract — Full Text

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4 citations

Alternative Name	Isolectin B4 (Griffonia simplicifolia), BSI-B4
Source	Isolated from Griffonia (Bandeiraea) simplicifolia seeds.

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Isolectin B₄ (Bandeiraea simplicifolia), (FITC conjugate)

ALX-650-001F

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Isolectin B4 (Bandeiraea simplicifolia), (FITC conjugate)

ALX-650-001F

Product Details

Handling & Storage

Related Products

Isolectin B4 (Bandeiraea simplicifolia), (biotin conjugate)

ALX-650-001B

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Isolectin B₄ (Bandeiraea simplicifolia), (FITC conjugate)

Isolectin B₄ (Bandeiraea simplicifolia), (biotin conjugate)