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Ingenol (high purity)

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PKC inhibitor

Extremely weak protein kinase C (PKC) activator. Starting material for synthesis of ingenol derivatives.

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Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Total synthesis of ingenol: I. Kuwajima & K. Tanino; Chem. Rev. 105, 4661 (2005), (Review), Abstract
Preconditioning of isolated rabbit cardiomyocytes: effects of glycolytic blockade, phorbol esters, and ischaemia: S. Armstrong & C.E. Gonote; Cardiovasc. Res. 28, 1700 (1994), Abstract
Specific binding to protein kinase C by ingenol and its induction of biological responses: C.M. Hasler, et al.; Cancer Res. 52, 202 (1992), Abstract

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