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Infigratinib Phosphate

LKT-I527211

Axxora Marketplace
  • LKT-I527211-M005   —   5 mg
    $213.00
  • LKT-I527211-M025   —   25 mg
    $434.00
  • LKT-I527211-M050   —   50 mg
    $698.00

NVP-BGJ398 is an inhibitor of FGFR that exhibits anticancer chemotherapeutic and antirachitic activities. NVP-BGJ398 inhibits cell viability in colon cancer cells and prevents progression and tumor formation in animal models of malignant rhabdoid tumors. In endometrial cancer cells, NVP-BGJ398 induces cell cycle arrest and inhibits growth; in vivo, it also inhibits tumor growth. NVP-BGJ398 inhibits aberrant FGFR signaling in animal models of rickets disease, normalizing bone growth and mineralization.

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Regulatory Status

RUO – Research Use Only