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Indirubin-3’-(2,3-dihydroxypropyl)oximether

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Src kinase inhibitor

Inhibitor of c-Src (IC₅₀=0.43µM) blocking downstream STAT3 signalling. Induces apoptosis in human cancer cells.

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Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Effects of the Indirubin Derivative E804 on Glioblastoma Associated Immunomodulation: H. Houke; , (2016), (master’s thesis), Application(s): Cytotoxicity assay and effects on protein expression, Full Text
Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells: S. Nam, et al.; PNAS 102, 5998 (2005), Abstract

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