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IL-33 is a member of the IL-1 family. It is involved in T helper type 2 response via the activation of its receptor ST2 (IL-1RL1) driving the production of Th2-associated cytokines. The stimulation of ST2 by IL-33 induces the NF-κB and MAPK pathways. The human IL-33 protein is expressed with a prodomain (aa 1-111) which is cleaved by caspase-1 to produce the 18kDa mature protein (112-270).
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Western Blot analysis: Lane 1: MW Marker; Lane 2: 100ng of purified IL-33 (rat), (recombinant) protein probed with IL-33 pAb (Prod. no. ALX-210-933) at 0.5μg/ml.
SDS-PAGE analysis: Lane 1: MW Marker; Lane 2: 1.0μg of purified IL-33 (rat), (recombinant).
| Regulatory Status |
RUO – Research Use Only |
|---|
Related Products
| Alternative Name | Interleukin-33, NF-HEV, IL-1F11 |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Untagged human IL-33 (aa 112-270). |
| Alternative Name | Interleukin-33, NF-HEV, IL-1F11 |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Untagged mouse IL-33 (aa 109-266). |
| Alternative Name | Interleukin-33, NF-HEV, IL-1F11 |
|---|---|
| Application | ELISA, WB |
| Host | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Alternative Name | Interleukin-33, IL-1F11, NF-HEV |
|---|---|
| Application | ELISA, IHC (PS), IP, WB |
| Host | Mouse |
| Isotype | IgG1κ |
| Species Reactivity | Human, Mouse, Rat |