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IL-33 polyclonal antibody (AT110)

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Alternative Name	Interleukin-33, NF-HEV, IL-1F11
Application	ELISA, WB
Formulation	Liquid. In PBS containing 0.02% sodium azide.
Gene/Protein Identifier	90865 (Entrez GeneID), 608678 (OMIM)
Host	Rabbit
Immunogen	Recombinant human soluble IL-33 (interleukin-33) (aa 112-270) (Prod. No. ALX-522-098).
Positive Control	Prod. No. ALX-522-098; Prod. No. ALX-522-101
Purity Detail	Protein A-affinity purified.
Recommendation Dilutions/Conditions	Western Blot (1:1,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Source	Purified from rabbit serum.
Species Reactivity	Human, Mouse, Rat
Specificity	Recognizes pro-IL-33 and mature IL-33.
UniProt ID	O95760
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Use/Stability	Stable for at least 1 year after receipt when stored at -20°C.
Handling	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Short Term Storage	+4°C
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats: C. Sitzia, et al.; Int. J. Mol. Sci. 24, 1991 (2023), Abstract
Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer’s disease: J. Chapuis, et al.; Mol. Psychiatry 14, 1004 (2009), Abstract
Nuclear Interleukin-33 Is Generally Expressed in Resting Endothelium but Rapidly Lost upon Angiogenic or Proinflammatory Activation: A.M. Küchler, et al.; Am. J. Pathol. 173, 1229 (2008), Abstract
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo: V. Carriere et al.; PNAS 104, 282 (2007), Abstract