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IL-33 monoclonal antibody (Nessy-1) (biotin conjugate)

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Alternative Name	Interleukin-33, IL-1F11, NF-HEV
Application	ELISA, IHC (PS)
Clone	Nessy-1
Formulation	Liquid. In PBS containing 0.02% sodium azide.
Gene/Protein Identifier	90865 (Entrez GeneID), 608678 (OMIM)
Host	Mouse
Immunogen	Recombinant human IL-33 (aa 112-270) (Prod. No. ALX-522-098).
Isotype	IgG1κ
Purity Detail	Protein G-affinity purified.
Source	Purified from ascites.
Species Reactivity	Human, Mouse, Rat
Specificity	Recognizes pro-IL-33 (precursor) and mature IL-33.
UniProt ID	O95760
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Use/Stability	Stable for at least 1 year after receipt when stored at -20°C.
Short Term Storage	+4°C
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease: Byers, D. E., Alexander-Brett, J., et al.; J. Clin. Invest. 123, 3967 (2013), Abstract
Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation: Ohno, T., Oboki, K., et al.; PLoS One 6, e18404 (2011), Abstract
Nuclear Interleukin-33 Is Generally Expressed in Resting Endothelium but Rapidly Lost upon Angiogenic or Proinflammatory Activation: A.M. Küchler, et al.; Am. J. Pathol. 173, 1229 (2008), Abstract