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Interleukin-3 (IL-3) is a cytokine produced by activated T cells and mast cells. IL-3 is able to induce the differentiation of hematopoietic stem cells to precursor cells of myeloid lineage (erythrocytes, megakaryocytes, granulocytes, dendritic cells and monocytes). IL-3 also has functions in the nervous system and appears to be important in several chronic inflammatory diseases.
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Figure 2: TF-1 cells were cultured with 0 to 100 ng/mL Human IL-3. Cell proliferation was measured after 72 hours and the linear portion of the curve can be used to calculate the ED50.
Figure 1: 1µg in each lane (-) non-reducing conditions and (+) reducing conditions in a 4-20% TRIS-Glycine gel, stained with Coomassie Blue. Human IL-3 has a predicted MW of 15 kDa.
| Regulatory Status |
RUO – Research Use Only |
|---|
Related Products
| Alternative Name | FMS-related tyrosine kinase 3 ligand |
|---|---|
| Purity | ≥95% (Reducing and Non-reducing SDS-PAGE) |
| Source | Produced in E. coli. Non-glycosylated protein, containing 155 amino acids. |
| Alternative Name | Interleukin-3, MCGF, Multi-CSF, HCGF, P-cell stimulation factor |
|---|---|
| Purity | ≥95% (reducing and non-reducing SDS-PAGE) |
| Source | Produced in E. coli. Non-glycosylated protein, containing 135 amino acids. |
Last modified: May 29, 2024