IL-22 receptor antagonist (E117A) (mouse), (recombinant)

Recombinant murine IL-22 E117A mutant is capable of full inhibition of STAT3 phosphorylation induced by mouse interleukin 22 in HepG cells. Its affinity toward immobilized mIL-22 receptor α1 extracellular domain (mIL-22 Rα1-ECD) or IL-22 binding protein is similar to the non mutated mouse interleukin 22. Mouse IL-22 antagonist (E117A) has very low agonistic activity in this bioassay.

< 0.1 ng/µg of protein (<1EU/µg)

Lyophilized.

16.7 kDa

> 98.0% as determined by Gel filtration and SDS-PAGE gel.

Produced in E. coli.

Q9JJY9