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Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover.
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RUO – Research Use Only |
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| Alternative Name | Interferon-λ-1, IL-29, Interleukin-29 |
|---|---|
| Purity | ≥98% (SDS-PAGE gel & HPLC) |
| Source | Produced in E.coli. |
| Alternative Name | IL-1RI, Interleukin-1 receptor type I, CD121a |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in HEK 293 cells. Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused to the Fc portion of human IgG1. |
| Alternative Name | Interleukin-10, Cytokine synthesis inhibitory factor, CSIF |
|---|---|
| Purity | ≥98% (SDS-PAGE gel & HPLC) |
| Source | Produced in E.coli. |
| Alternative Name | Interleukin-10, Cytokine synthesis inhibitory factor, CSIF |
|---|---|
| Purity | ≥98% (SDS-PAGE gel & HPLC) |
| Source | Produced in E.coli. |